(2Z,4E)-3-methyl-2,4-hexadienedioic acid

Base Information

• Chemical Name: (2Z,4E)-3-methyl-2,4-hexadienedioic acid
• CAS No.: 31659-59-3
• Molecular Formula: C₇H₈O₄
• Molecular Weight: 156.138
• Mol file: 31659-59-3.mol

Synonyms:(2Z,4E)-3-methyl-2,4-hexadienedioic acid

Chemical Property of (2Z,4E)-3-methyl-2,4-hexadienedioic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2Z,4E)-3-methyl-2,4-hexadienedioic acid

There total 5 articles about (2Z,4E)-3-methyl-2,4-hexadienedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

4-methyl-1,2-dihydroxybenzene (452-86-8) → 4-methyl-5-carboxymethyl-2-furanone (6307-98-8) + (2Z,4E)-3-methyl-2,4-hexadienedioic acid (31659-59-3)

Guidance literature:

With formic acid; Peroxyformic acid; ferrous ammonium sulphate hexahydrate; In water; for 22h; Green chemistry;

DOI:10.1039/d0gc02157a

Reference yield:

2-Methoxy-4-methylphenol (93-51-6) → citraconic acid (498-23-7,7407-59-2) + 2-methylbutanedioic acid (498-21-5,636-60-2) + 2-hydroxy-2-methylbutane-1,4-dioic acid (597-44-4,2306-22-1) + malonic acid (141-82-2) + 3-methylhexa-2,4 dienedioic acid (31659-59-3,76799-85-4,116672-65-2,17110-47-3) + oxalic acid (144-62-7,97993-78-7)

Guidance literature:

With sodium hydroxide; oxygen; at 45 ℃; for 1.5h; under 63755.1 Torr; Product distribution; Mechanism; var. temp., time, O₂ pressure, conc. and amount of NaOH, different amounts of creosol;

DOI:10.1007/BF00909659

Reference yield:

4-methyl-1,2-dihydroxybenzene (452-86-8) → 4-methyl-5-carboxymethyl-2-furanone (6307-98-8) + (2Z,4E)-3-methyl-2,4-hexadienedioic acid (31659-59-3)

Guidance literature:

unter Lichtausschluss;

upstream raw materials:

4-methyl-1,2-dihydroxybenzene

dihydrogen peroxide

acetic anhydride

acetic acid

Downstream raw materials:

4-methyl-5-carboxymethyl-2-furanone

3-methyladipic acid

citraconic acid

2-methylbutanedioic acid

Refernces

• 1、 McKague, A. Bruce. "Synthesis of muconic acids peracetic acid oxidation of catechols". . p. 1463 - 1475. Retrieved 2007/10/03.