tert-Butyldimethylsilyl N-Phenylbenzimidate

Base Information

• Chemical Name: tert-Butyldimethylsilyl N-Phenylbenzimidate
• CAS No.: 404392-70-7
• Molecular Formula: C19H25 N O Si
• Molecular Weight: 311.499
• Hs Code.: 2931900090
• European Community (EC) Number: 678-169-0
• DSSTox Substance ID: DTXSID20458504
• Nikkaji Number: J1.646.864I
• Mol file: 404392-70-7.mol

Synonyms:tert-Butyldimethylsilyl N-Phenylbenzimidate;[tert-butyl(dimethyl)silyl] N-phenylbenzenecarboximidate;t-Butyldimethylsilyl-N-phenylbenzimidate;O-(tert-Butyldimethylsilyl)benzanilide;TBDMS-BEZA;DTXSID20458504;MFCD08276306;AKOS015840688;AKOS025295298;tert-ButyldimethylsilylN-Phenylbenzimidate;B2697;T70885;N-Phenylbenzenecarbimidic acid tert-butyldimethylsilyl ester

Chemical Property of tert-Butyldimethylsilyl N-Phenylbenzimidate

Chemical Property:

• Vapor Pressure: 1.95E-05mmHg at 25°C
• Melting Point: 71 °C
• Refractive Index: 1.501
• Boiling Point: 373.3°C at 760 mmHg
• PKA: 2.31±0.50(Predicted)
• Flash Point: 179.5°C
• PSA: 21.59000
• Density: 0.93g/cm³
• LogP: 5.78670
• Solubility.: soluble in Methanol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 311.170540955
• Heavy Atom Count: 22
• Complexity: 371

Purity/Quality:

98%,99%, ^*data from raw suppliers

tert-Butyldimethylsilyl N-Phenylbenzimidate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)[Si](C)(C)OC(=NC1=CC=CC=C1)C2=CC=CC=C2

Technology Process of tert-Butyldimethylsilyl N-Phenylbenzimidate

There total 1 articles about tert-Butyldimethylsilyl N-Phenylbenzimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

N-phenyl benzoyl amide (93-98-1,5705-51-1) + tert-butyldimethylsilyl chloride (18162-48-6) → tert-butyldimethylsilyl N-phenylbenzimidate (404392-70-7)

Guidance literature:

N-phenyl benzoyl amide; With sodium hydride; In acetonitrile; at 20 - 25 ℃; for 1h;

tert-butyldimethylsilyl chloride; In acetonitrile; at 20 - 25 ℃; Further stages.;

DOI:10.1039/b107447b

Reference yield: 99.0%

2,4-di-tert-Butylphenol (96-76-4) + tert-butyldimethylsilyl N-phenylbenzimidate (404392-70-7) → tert-butyl-(2,4-di-tert-butyl-phenoxy)-dimethyl-silane

Guidance literature:

With pyridinium triflate; In various solvent(s); at 50 ℃; for 1h;

DOI:10.1039/b107447b

Reference yield: 96.0%

TERPINEN-4-OL (562-74-3) + tert-butyldimethylsilyl N-phenylbenzimidate (404392-70-7) → 1-(tert-butyldimethylsilyloxy)-1-isopropyl-4-methyl-3-cyclohexene

Guidance literature:

With pyridinium triflate; In tetrahydrofuran; at 50 ℃; for 2.5h;

DOI:10.1039/b107447b

upstream raw materials:

N-phenyl benzoyl amide

tert-butyldimethylsilyl chloride

Refernces