CID 11882158

Base Information

• Chemical Name: CID 11882158
• CAS No.: 49805-32-5
• Molecular Formula: C₆H₁₁NO₂
• Molecular Weight: 129.159
• Mol file: 49805-32-5.mol

Synonyms:SCHEMBL22800565

Chemical Property of CID 11882158

Chemical Property:

• Boiling Point: 264.7±33.0 °C(Predicted)
• PKA: 4.44±0.20(Predicted)
• PSA: 63.32000
• Density: 1.190±0.06 g/cm3(Predicted)
• LogP: 0.89870
• Storage Temp.: 2-8°C
• XLogP3: -1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 129.078978594
• Heavy Atom Count: 9
• Complexity: 119

Purity/Quality:

≥95% ^*data from raw suppliers

cis-3-Amino-cyclopentanecarboxylicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(CC1C(=O)[O-])[NH3+]
• Isomeric SMILES: C1C[C@@H](C[C@@H]1C(=O)[O-])[NH3+]

Technology Process of CID 11882158

There total 26 articles about CID 11882158 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

trans-4-aminocyclopent-2-ene-1-carboxylic acid → trans-3-aminocyclopentane-1-carboxylic acid (19042-34-3,19297-28-0,49805-32-5,57376-72-4,71376-02-8,71830-07-4,71830-08-5,71869-43-7,89614-96-0)

Guidance literature:

With hydrogen; 10% palladium on active carbon; In acetic acid; Ambient temperature;

DOI:10.1071/CH9860855

Reference yield: 81.0%

cis-4-amino-cyclopent-2-ene-1-carboxylic acid (102579-71-5,102579-72-6,102679-78-7,134003-04-6,134234-04-1) → cis-3-aminocyclopentane-1-carboxylic acid (49805-32-5)

Guidance literature:

With hydrogen; palladium on activated charcoal; In acetic acid; Ambient temperature;

DOI:10.1071/CH9860855

Reference yield: 78.0%

trans-3-phthalimidocyclopentane-1-carboxylic acid → trans-3-aminocyclopentane-1-carboxylic acid (19042-34-3,19297-28-0,49805-32-5,57376-72-4,71376-02-8,71830-07-4,71830-08-5,71869-43-7,89614-96-0)

Guidance literature:

With hydrazine; In methanol; Heating;

DOI:10.1071/CH9860855

upstream raw materials:

methyl 3-aminocyclopentane-1-carboxylate

3-tosyl-2-azabicyclo [2.2.1]hepta-2,5-diene

cis-4-amino-cyclopent-2-ene-1-carboxylic acid

cyclopent-1-enecarbonitrile

Downstream raw materials:

cis-N-(2-Cyanoethyl)-3-benzyloxycarbonylamino-cyclopentan-carbonamid

(+/-)-β--propionamidin

cis-N-Methyl-N-(2-cyanoethyl)-3-benzyloxycarbonylamino-cyclopentan-carbonamid

cis-N-(2-Carbamoyl-ethyl)-3-benzyloxycarbonylamino-cyclopentan-carbonamid

Refernces

• 1、 Allan,Twitchin. "Synthesis of analogues of GABA. IV. Three unsaturated derivatives of 3-aminocyclopentane-1-carboxylic acid". . p. 599 - 604. Retrieved 2007/10/02.