C₁₅H₁₅NO₃

Base Information

• Chemical Name: C₁₅H₁₅NO₃
• CAS No.: 1361938-29-5
• Molecular Formula: C₁₅H₁₅NO₃
• Molecular Weight: 257.289
• Mol file: 1361938-29-5.mol

Synonyms:C₁₅H₁₅NO₃

Chemical Property of C₁₅H₁₅NO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₅H₁₅NO₃

There total 3 articles about C₁₅H₁₅NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 3-methyl-1H-pyrrole-2-carboxylate (3284-47-7) + benzoyl chloride (98-88-4) → C15H15NO3 (1361938-29-5) + ethyl 4-benzoyl-3-methylpyrrole-2-carboxylate (112381-11-0)

Guidance literature:

With zinc(II) chloride; In 1,2-dichloro-ethane; for 2h; Reflux;

Reference yield:

ethyl 3-hydroxy-3-methyl-1-p-toluenesulfonylpyrrolidine-2-carboxylate (3284-52-4) → C15H15NO3 (1361938-29-5) + ethyl 4-benzoyl-3-methylpyrrole-2-carboxylate (112381-11-0)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine; trichlorophosphate / 72 h / 20 °C / Cooling with ice

2: sodium ethanolate / ethanol

3: zinc(II) chloride / 1,2-dichloro-ethane / 2 h / Reflux

With pyridine; sodium ethanolate; zinc(II) chloride; trichlorophosphate; In ethanol; 1,2-dichloro-ethane;

Reference yield:

3-methyl-1-p-toluenesulfonyl-2,5-dihydro-1H-pyrrole-2-carboxylic acid ethyl ester (3284-53-5) → C15H15NO3 (1361938-29-5) + ethyl 4-benzoyl-3-methylpyrrole-2-carboxylate (112381-11-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium ethanolate / ethanol

2: zinc(II) chloride / 1,2-dichloro-ethane / 2 h / Reflux

With sodium ethanolate; zinc(II) chloride; In ethanol; 1,2-dichloro-ethane;

upstream raw materials:

ethyl 3-hydroxy-3-methyl-1-p-toluenesulfonylpyrrolidine-2-carboxylate

3-methyl-1-p-toluenesulfonyl-2,5-dihydro-1H-pyrrole-2-carboxylic acid ethyl ester

ethyl 3-methyl-1H-pyrrole-2-carboxylate

benzoyl chloride

Refernces