Technology Process of 2-([1,1'-biphenyl]-4-yl)-N-benzyl-N-methylacetamide
There total 3 articles about 2-([1,1'-biphenyl]-4-yl)-N-benzyl-N-methylacetamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide;
In
ethyl acetate;
at 0 - 20 ℃;
DOI:10.1021/ml5000564
- Guidance literature:
-
With
oxone||potassium monopersulfate triple salt; sodium hydrogencarbonate;
In
N,N-dimethyl-formamide;
at 50 ℃;
for 12h;
Inert atmosphere;
DOI:10.1002/anie.202000988
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere
1.2: 2 h / -78 °C / Inert atmosphere
2.1: oxone||potassium monopersulfate triple salt; sodium hydrogencarbonate / N,N-dimethyl-formamide / 12 h / 50 °C / Inert atmosphere
With
n-butyllithium; oxone||potassium monopersulfate triple salt; sodium hydrogencarbonate;
In
tetrahydrofuran; hexane; N,N-dimethyl-formamide;
DOI:10.1002/anie.202000988
