Technology Process of Benzofuran, 3-(2R)-oxiranyl- (9CI)
There total 6 articles about Benzofuran, 3-(2R)-oxiranyl- (9CI) which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 60 percent / pyridinium tribromide / acetic acid / 1 h / 20 °C
2: 9.37 g / (-)-B-chlorodiisopinocampheylborane / tetrahydrofuran / 26 h / -30 - 20 °C
3: sodium hydride / tetrahydrofuran / 3 h / 20 °C
With
sodium hydride; pyridinium hydrobromide perbromide; (-)-diisopinocamphenylborane chloride;
In
tetrahydrofuran; acetic acid;
DOI:10.3987/COM-00-9143
- Guidance literature:
-
With
sodium hydride;
In
tetrahydrofuran;
at 20 ℃;
for 3h;
Title compound not separated from byproducts;
DOI:10.3987/COM-00-9143
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 77 percent / selenium dioxide / dioxane / 48 h / Heating
2: diethyl ether / 20 °C
3: 6.80 g / pyridinium chlorochromate / CH2Cl2 / 10 h / 20 °C
4: 60 percent / pyridinium tribromide / acetic acid / 1 h / 20 °C
5: 9.37 g / (-)-B-chlorodiisopinocampheylborane / tetrahydrofuran / 26 h / -30 - 20 °C
6: sodium hydride / tetrahydrofuran / 3 h / 20 °C
With
selenium(IV) oxide; sodium hydride; pyridinium hydrobromide perbromide; (-)-diisopinocamphenylborane chloride; pyridinium chlorochromate;
In
tetrahydrofuran; 1,4-dioxane; diethyl ether; dichloromethane; acetic acid;
DOI:10.3987/COM-00-9143