1-Naphthoic anhydride

Base Information

• Chemical Name: 1-Naphthoic anhydride
• CAS No.: 64985-86-0
• Molecular Formula: C22H14 O3
• Molecular Weight: 326.351
• Hs Code.: 2916399090
• Mol file: 64985-86-0.mol

Synonyms:1-Naphthalenecarboxylicacid, anhydride (9CI); 1-Naphthoic anhydride (6CI,7CI); NSC 509713

Chemical Property of 1-Naphthoic anhydride

Chemical Property:

• Vapor Pressure: 1.14E-11mmHg at 25°C
• Melting Point: 138-142 °C
• Boiling Point: 538.6°C at 760 mmHg
• Flash Point: 269.2°C
• PSA: 43.37000
• Density: 1.279g/cm³
• LogP: 4.99020

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Naphthoic anhydride

There total 9 articles about 1-Naphthoic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1-naphthalenecarboxylic acid (86-55-5) → 1-naphthoic anhydride (64985-86-0)

Guidance literature:

With potassium carbonate; p-toluenesulfonyl chloride; In ethyl acetate; at 20 ℃; for 0.416667h;

DOI:10.1055/s-2003-44381

Reference yield: 90.0%

1-naphthalene methanol (4780-79-4) → 1-naphthoic anhydride (64985-86-0)

Guidance literature:

With tert.-butylhydroperoxide; tetrabutyl phosphonium bromide; In water; chlorobenzene; at 80 ℃; for 2.5h; Sealed tube;

DOI:10.1055/s-0036-1590905

Reference yield: 70.0%

1-naphthaldehyde (66-77-3) → 1-naphthoic anhydride (64985-86-0)

Guidance literature:

With tert.-butylhydroperoxide; tetrabutyl phosphonium bromide; In chlorobenzene; at 80 ℃; for 3h; Sealed tube;

DOI:10.1016/j.tetlet.2016.05.069

upstream raw materials:

naphthalene-1-carbonic acid chloride

naphthalene

carbon monoxide

1-naphthalenecarboxylic acid

Downstream raw materials:

phenylethyl 1-naphthoate

1-phenylethyl 1-naphthoate

1-(4-methoxyphenyl)naphthalene

1-naphthalenecarbonyl fluoride

Refernces

• 1、 Mayr, Stefanie,Zipse, Hendrik. "Size-Induced Inversion of Selectivity in the Acylation of 1,2-Diols". supporting information. p. 18084 - 18092. Retrieved 2021/12/02.
• 2、 Eskandari, Parvin,Kazemi, Foad. "An investigation on practical synthesis of carboxylic acid derivatives using p-toluenesulfonyl chloride". . p. 431 - 439. Retrieved 2017/07/24.