d5-(2,2-dicarboxy-2-acetamidoethyl)benzeneboronic acid

Base Information

• Chemical Name: d5-(2,2-dicarboxy-2-acetamidoethyl)benzeneboronic acid
• CAS No.: 936247-99-3
• Molecular Formula: C₁₂H₁₄BNO₇
• Molecular Weight: 300.017
• Mol file: 936247-99-3.mol

Synonyms:d5-(2,2-dicarboxy-2-acetamidoethyl)benzeneboronic acid

Chemical Property of d5-(2,2-dicarboxy-2-acetamidoethyl)benzeneboronic acid

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of d5-(2,2-dicarboxy-2-acetamidoethyl)benzeneboronic acid

There total 2 articles about d5-(2,2-dicarboxy-2-acetamidoethyl)benzeneboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

acetylamino-(4-dihydroxyboranyl-benzyl)-malonic acid diethyl ester (101269-67-4) → d5-(2,2-dicarboxy-2-acetamidoethyl)benzeneboronic acid (936247-99-3)

Guidance literature:

acetylamino-(4-dihydroxyboranyl-benzyl)-malonic acid diethyl ester; With deuteriated sodium hydroxide; In water-d2; at 20 ℃; for 3h;

With hydrogen chloride; In water-d2; for 3h; Product distribution / selectivity;

Reference yield: 94.0%

(2,2-dicarboxy-2-acetamidoethyl)benzeneboronic acid → d5-(2,2-dicarboxy-2-acetamidoethyl)benzeneboronic acid (936247-99-3)

Guidance literature:

(2,2-dicarboxy-2-acetamidoethyl)benzeneboronic acid; With deuteriated sodium hydroxide; In water-d2;

With hydrogen chloride; In water-d2; for 2h; Product distribution / selectivity;

Reference yield: 81.0%

d5-(2,2-dicarboxy-2-acetamidoethyl)benzeneboronic acid (936247-99-3) → d6-4-boronophenylalanine (80994-59-8)

Guidance literature:

d5-(2,2-dicarboxy-2-acetamidoethyl)benzeneboronic acid; With hydrogen chloride; In water-d2; at 90 - 100 ℃; Heating / reflux;

With deuteriated sodium hydroxide; In water-d2; Product distribution / selectivity;

upstream raw materials:

acetylamino-(4-dihydroxyboranyl-benzyl)-malonic acid diethyl ester

Downstream raw materials:

d6-4-boronophenylalanine

Refernces