fluoroacetyl-coenzyme A

Base Information

• Chemical Name: fluoroacetyl-coenzyme A
• CAS No.: 485-13-2
• Molecular Formula: C23H37 F N7 O17 P3 S
• Molecular Weight: 827.569
• Mol file: 485-13-2.mol

Synonyms:Coenzyme A,fluoroacetate (6CI); Fluoroacetyl-CoA

Chemical Property of fluoroacetyl-coenzyme A

Chemical Property:

• PKA: 1.16±0.50(Predicted)
• PSA: 425.34000
• Density: 1.92±0.1 g/cm3(Predicted)
• LogP: 0.89600

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of fluoroacetyl-coenzyme A

There total 3 articles about fluoroacetyl-coenzyme A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

coenzyme A trilithium salt + sodium fluoroacetate (62-74-8) → fluoroacetyl coenzyme A (485-13-2)

Guidance literature:

sodium fluoroacetate; With oxalyl dichloride; In tetrahydrofuran; N,N-dimethyl-formamide; at 65 ℃; Inert atmosphere;

coenzyme A trilithium salt; With sodium hydrogencarbonate; In tetrahydrofuran; water; N,N-dimethyl-formamide; for 0.05h; Inert atmosphere;

DOI:10.1021/bi101102u

Reference yield:

coenzyme A (85-61-0) → fluoroacetyl coenzyme A (485-13-2)

Guidance literature:

Reference yield:

2-fluoroacetic acid anhydride (407-33-0) + coenzyme A (85-61-0) → fluoroacetyl coenzyme A (485-13-2)

Guidance literature:

upstream raw materials:

2-fluoroacetic acid anhydride

coenzyme A

sodium fluoroacetate

Downstream raw materials:

coenzyme A

Refernces