4ALPHA-METHYL-5ALPHA(H),14ALPHA(H),17ALPHA(H)-CHOLESTANE

Base Information

• Chemical Name: 4ALPHA-METHYL-5ALPHA(H),14ALPHA(H),17ALPHA(H)-CHOLESTANE
• CAS No.: 474-41-9
• Molecular Formula: C₂₈H₅₀
• Molecular Weight: 386.705
• Mol file: 474-41-9.mol

Synonyms:5a-Cholestane, 4a-methyl- (6CI,8CI); 4a-Methyl-5a-cholestane; Lophane

Chemical Property of 4ALPHA-METHYL-5ALPHA(H),14ALPHA(H),17ALPHA(H)-CHOLESTANE

Chemical Property:

• PSA: 0.00000
• LogP: 8.74380

Purity/Quality:

99% ^*data from raw suppliers

4ALPHA-METHYL-5ALPHA(H),14ALPHA(H),17ALPHA(H)-CHOLESTANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4ALPHA-METHYL-5ALPHA(H),14ALPHA(H),17ALPHA(H)-CHOLESTANE

There total 4 articles about 4ALPHA-METHYL-5ALPHA(H),14ALPHA(H),17ALPHA(H)-CHOLESTANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4α-methyl-5α-cholestan-3-one (984-87-2) → 4α-methyl-5α-cholestane (474-41-9)

Guidance literature:

With sodium; hydrazine hydrate; diethylene glycol;

DOI:10.1021/ja01556a031

Reference yield:

cholest-4α-methyl-7-en-3β-ol acetate (6702-46-1) → 4α-methyl-5α-cholestane (474-41-9)

Guidance literature:

Multi-step reaction with 3 steps

1: platinum; aqueous HCl; acetic acid / Hydrogenation_.Behandeln des Reaktionsprodukts mit methanol. KOH

2: CrO₃; H₂SO₄; acetic acid / in Aceton

3: hydrazine hydrate; diethylene glycol; sodium

With chromium(VI) oxide; hydrogenchloride; sulfuric acid; sodium; hydrazine hydrate; acetic acid; platinum; diethylene glycol;

DOI:10.1021/ja01556a031

Reference yield:

(3β,4α,5α)-4-methylcholestan-3-ol (3903-57-9) → 4α-methyl-5α-cholestane (474-41-9)

Guidance literature:

Multi-step reaction with 2 steps

1: CrO₃; H₂SO₄; acetic acid / in Aceton

2: hydrazine hydrate; diethylene glycol; sodium

With chromium(VI) oxide; sulfuric acid; sodium; hydrazine hydrate; acetic acid; diethylene glycol;

DOI:10.1021/ja01556a031

upstream raw materials:

4α-methyl-5α-cholestan-3-one

cholest-4α-methyl-7-en-3β-ol acetate

(3β,4α,5α)-4-methylcholestan-3-ol