benzoyloxy-3β (anisalamino-4' urazolo-1',2')-5α,8α ergostadiene-6,22

Base Information

• Chemical Name: benzoyloxy-3β (anisalamino-4' urazolo-1',2')-5α,8α ergostadiene-6,22
• CAS No.: 87530-77-6
• Molecular Formula: C₄₅H₅₆N₄O₅
• Molecular Weight: 732.963
• Mol file: 87530-77-6.mol

Synonyms:benzoyloxy-3β (anisalamino-4' urazolo-1',2')-5α,8α ergostadiene-6,22

Chemical Property of benzoyloxy-3β (anisalamino-4' urazolo-1',2')-5α,8α ergostadiene-6,22

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzoyloxy-3β (anisalamino-4' urazolo-1',2')-5α,8α ergostadiene-6,22

There total 2 articles about benzoyloxy-3β (anisalamino-4' urazolo-1',2')-5α,8α ergostadiene-6,22 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

(3β,22E)-ergosta-5,7,22-trien-3-ol benzoate (5035-30-3) + p-methoxybenzalamino-4 urazole (87530-73-2) → benzoyloxy-3β (anisalamino-4' urazolo-1',2')-5α,8α ergostadiene-6,22 (87530-77-6)

Guidance literature:

With (PhSeO)2O; In tetrahydrofuran; for 2h; Product distribution; Ambient temperature; various reagents;

Reference yield:

4-methoxy-benzaldehyde (123-11-5) → benzoyloxy-3β (anisalamino-4' urazolo-1',2')-5α,8α ergostadiene-6,22 (87530-77-6)

Guidance literature:

Multi-step reaction with 2 steps

1: water / 0.5 h / Reflux

2: sodium nitrite; acetic acid / ethyl acetate / 0.08 h / 20 °C / Inert atmosphere

With acetic acid; sodium nitrite; In water; ethyl acetate;

DOI:10.3987/COM-12-12637

Reference yield: 98.0%

benzoyloxy-3β (anisalamino-4' urazolo-1',2')-5α,8α ergostadiene-6,22 (87530-77-6) → benzoyloxy-3β (urazolo-1',2')-5α,8α ergostadiene-6,22 (87530-75-4)

Guidance literature:

With sodium nitrite; In tetrahydrofuran; acetic acid;

upstream raw materials:

(3β,22E)-ergosta-5,7,22-trien-3-ol benzoate

p-methoxybenzalamino-4 urazole

4-methoxy-benzaldehyde

Downstream raw materials:

Ergosterol

benzoyloxy-3β (urazolo-1',2')-5α,8α ergostadiene-6,22

benzoyloxy-3β (amino-4' urazolo-1',2')-5α,8α ergostadiene-6,22

(p-nitrophenyl-4' urazolo-1',2')-5α,8α ergostadiene-6,22 ol-3β

Refernces

• 1、 Barton,Lusinchi,Sandoval Ramirez. "Protection of the diene system of ergosterol by formation of urazole adducts: Comparative action of phenylaleninic anhydride on urazole derivatives and ergosterol: Influence of structure of the adduct". . p. 849 - 858. Retrieved 2007/10/02.