1,1,2,2-tetrafluoroethanesulfonic Acid

Base Information

• Chemical Name: 1,1,2,2-tetrafluoroethanesulfonic Acid
• CAS No.: 464-14-2
• Molecular Formula: C2H2 F4 O3 S
• Molecular Weight: 182.096
• Hs Code.: 2904909090
• European Community (EC) Number: 628-715-9
• DSSTox Substance ID: DTXSID90436415
• Nikkaji Number: J2.258.836B
• Wikidata: Q81985952
• Mol file: 464-14-2.mol

Synonyms:1,1,2,2-tetrafluoroethane-1-sulfonic acid;1,1,2,2-tetrafluoroethanesulfonic acid

Chemical Property of 1,1,2,2-tetrafluoroethanesulfonic Acid

Chemical Property:

• Refractive Index: n20/D 1.354
• Boiling Point: 250°C
• PKA: -3.50±0.50(Predicted)
• PSA: 62.75000
• Density: 1.7
• LogP: 1.81290
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 2
• Exact Mass: 181.96607774
• Heavy Atom Count: 10
• Complexity: 201

Purity/Quality:

98%Min ^*data from raw suppliers

1,1,2,2-TETRAFLUOROETHANESULFONIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 21/22-35
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C(F)(F)S(=O)(=O)O)(F)F

Technology Process of 1,1,2,2-tetrafluoroethanesulfonic Acid

There total 1 articles about 1,1,2,2-tetrafluoroethanesulfonic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

polytetrafluoroethylene (116-14-3,82785-14-6) → Difluoroacetic acid (381-73-7) + 1,1,2,2-tetrafluoroethanesulfonic acid (464-14-2)

Guidance literature:

With sodium sulfite; at 120 ℃; under 18387.7 Torr;

Reference yield: 99.0%

1,1,2,2-tetrafluoroethanesulfonic acid (464-14-2) + phenylacetylene (536-74-3) → 1-phenylvinyl 1,1,2,2-tetrafluoroethane-1-sulfonate

Guidance literature:

With chloro(1,5-cyclooctadiene)rhodium(I) dimer; triphenylphosphine; In 1,2-dichloro-ethane; at 70 ℃; for 1.5h; regioselective reaction;

DOI:10.1002/cctc.201300228

Reference yield: 81.0%

4-n-chlorophenylacetylene (873-73-4) + 1,1,2,2-tetrafluoroethanesulfonic acid (464-14-2) → 1-(4-chlorophenyl)-3,3,4,4-tetrafluorobutan-1-one

Guidance literature:

With 2,2'-azobis(isobutyronitrile); In 1,2-dichloro-ethane; at 80 ℃; for 4h; Inert atmosphere;

upstream raw materials:

polytetrafluoroethylene