Technology Process of (4'-methoxyphenyl)-2-naphthyliodonium-3-carboxylate
There total 4 articles about (4'-methoxyphenyl)-2-naphthyliodonium-3-carboxylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) NaOH; 2.) 1N NaOH; 3.) conc. HCl, potassium iodide, iodine / 1.) water, glacial acetic acid, 170 deg C, 70 h; 2.) water, heating to boiling; 3.) glacial acetic acid, water, reflux, 5 min
2: 85 percent / chlorine / CHCl3 / 1 h / 0 °C
3: 1.) aq. NaOH; 2.) dild. H2SO4 / 1.) r.t.; 2.) r.t.
4: 1.) peracetic acid, trifluoroacetic acid, H2SO4; 2.) KOH / 1.) 70-80 deg C, 2.5 h; 2.) water
With
hydrogenchloride; peracetic acid; potassium hydroxide; sodium hydroxide; sulfuric acid; iodine; chlorine; trifluoroacetic acid; potassium iodide;
In
chloroform;
DOI:10.1016/S0040-4020(01)85138-3
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 85 percent / chlorine / CHCl3 / 1 h / 0 °C
2: 1.) aq. NaOH; 2.) dild. H2SO4 / 1.) r.t.; 2.) r.t.
3: 1.) peracetic acid, trifluoroacetic acid, H2SO4; 2.) KOH / 1.) 70-80 deg C, 2.5 h; 2.) water
With
peracetic acid; potassium hydroxide; sodium hydroxide; sulfuric acid; chlorine; trifluoroacetic acid;
In
chloroform;
DOI:10.1016/S0040-4020(01)85138-3
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) aq. NaOH; 2.) dild. H2SO4 / 1.) r.t.; 2.) r.t.
2: 1.) peracetic acid, trifluoroacetic acid, H2SO4; 2.) KOH / 1.) 70-80 deg C, 2.5 h; 2.) water
With
peracetic acid; potassium hydroxide; sodium hydroxide; sulfuric acid; trifluoroacetic acid;
DOI:10.1016/S0040-4020(01)85138-3
