C₈₄H₁₁₈N₁₆O₃₅

Base Information

• Chemical Name: C₈₄H₁₁₈N₁₆O₃₅
• CAS No.: 1217351-10-4
• Molecular Formula: C₈₄H₁₁₈N₁₆O₃₅
• Molecular Weight: 1911.95
• Mol file: 1217351-10-4.mol

Synonyms:C₈₄H₁₁₈N₁₆O₃₅

Chemical Property of C₈₄H₁₁₈N₁₆O₃₅

Chemical Property:

Purity/Quality:

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Technology Process of C₈₄H₁₁₈N₁₆O₃₅

There total 1 articles about C₈₄H₁₁₈N₁₆O₃₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azapentacosan-25-oic acid (882847-34-9,850312-72-0) + 2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(9-oxo-9,10-dihydro-acridin-2-yl)-propionic acid (1013328-63-6) + N-Fmoc-Tyr-OH (112883-29-1,92954-90-0) + N-α-9-fluorenylmethoxycarbonyl-aspartic acid (136083-57-3,136083-73-3,119062-05-4) + (S)-2-[{({9H-fluoren-9-yl}methoxy)carbonyl}amino]pentanedioic acid (104091-09-0,136083-74-4,121343-82-6) + acetic anhydride (108-24-7) + 9-fluorenylmethoxycarbonyl-L-alanine hydrochloride (139262-23-0) → C84H118N16O35 (1217351-10-4)

Guidance literature:

Fmoc-SH-SAL-PEG resin; With piperidine; In N,N-dimethyl-formamide; at 20 ℃; for 0.166667h; solid phase reaction;

9-fluorenylmethoxycarbonyl-L-alanine hydrochloride; With 1-hydroxy-7-aza-benzotriazole; N-ethyl-N,N-diisopropylamine; HATU; In 1-methyl-pyrrolidin-2-one; at 45 ℃; for 1h; solid phase reaction;

1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azapentacosan-25-oic acid; 2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(9-oxo-9,10-dihydro-acridin-2-yl)-propionic acid; N-Fmoc-Tyr-OH; N-α-9-fluorenylmethoxycarbonyl-aspartic acid; (S)-2-[{({9H-fluoren-9-yl}methoxy)carbonyl}amino]pentanedioic acid; acetic anhydride; Further stages;

DOI:10.1039/b920426a

upstream raw materials:

1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azapentacosan-25-oic acid

2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(9-oxo-9,10-dihydro-acridin-2-yl)-propionic acid

N-Fmoc-Tyr-OH

N-α-9-fluorenylmethoxycarbonyl-aspartic acid

Refernces