tri-O-(2-hydroxyethyl)-O-tosylpentaerythritol

Base Information

• Chemical Name: tri-O-(2-hydroxyethyl)-O-tosylpentaerythritol
• CAS No.: 882516-56-5
• Molecular Formula: C₁₈H₃₀O₉S
• Molecular Weight: 422.497
• Mol file: 882516-56-5.mol

Synonyms:tri-O-(2-hydroxyethyl)-O-tosylpentaerythritol

Chemical Property of tri-O-(2-hydroxyethyl)-O-tosylpentaerythritol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tri-O-(2-hydroxyethyl)-O-tosylpentaerythritol

There total 3 articles about tri-O-(2-hydroxyethyl)-O-tosylpentaerythritol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

1,3-bis(allyloxy)-2-allyloxymethyl-2-[(p-toluenesulfonyloxy)methyl]propane (879015-64-2) → tri-O-(2-hydroxyethyl)-O-tosylpentaerythritol (882516-56-5)

Guidance literature:

1,3-bis(allyloxy)-2-allyloxymethyl-2-[(p-toluenesulfonyloxy)methyl]propane; With ozone; In methanol; dichloromethane; at -78 ℃;

With sodium tetrahydroborate; In methanol; dichloromethane; at 0 - 20 ℃;

DOI:10.1002/ejoc.200500692

Reference yield:

pentaerythritol triallyl ether (1471-17-6) → tri-O-(2-hydroxyethyl)-O-tosylpentaerythritol (882516-56-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 81 percent / pyridine / 20 °C

2.1: O₃ / methanol; CH₂Cl₂ / -78 °C

2.2: 46 percent / NaBH₄ / methanol; CH₂Cl₂ / 0 - 20 °C

With pyridine; ozone; In methanol; dichloromethane;

DOI:10.1002/ejoc.200500692

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → tri-O-(2-hydroxyethyl)-O-tosylpentaerythritol (882516-56-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 81 percent / pyridine / 20 °C

2.1: O₃ / methanol; CH₂Cl₂ / -78 °C

2.2: 46 percent / NaBH₄ / methanol; CH₂Cl₂ / 0 - 20 °C

With pyridine; ozone; In methanol; dichloromethane;

DOI:10.1002/ejoc.200500692

upstream raw materials:

1,3-bis(allyloxy)-2-allyloxymethyl-2-[(p-toluenesulfonyloxy)methyl]propane

pentaerythritol triallyl ether

p-toluenesulfonyl chloride

Downstream raw materials:

tri-O-(2-acetoxyethyl)-O-tosylpentaerythritol

Refernces