2,2-Bis(trifluoromethyl)oxirane

Base Information

• Chemical Name: 2,2-Bis(trifluoromethyl)oxirane
• CAS No.: 31898-68-7
• Molecular Formula: C4H2F6O
• Molecular Weight: 180.05
• Hs Code.: 2910900090
• Mol file: 31898-68-7.mol

Synonyms:Propane,2,3-epoxy-1,1,1-trifluoro-2-(trifluoromethyl)- (8CI);2,2-Bis(trifluoromethyl)oxirane;Hexafluoroisobutylene oxide;2,2-bis(trifluoromethyl)oxirane;oxirane, 2,2-bis(trifluoromethyl)-;

Chemical Property of 2,2-Bis(trifluoromethyl)oxirane

Chemical Property:

• Vapor Pressure: 523.193mmHg at 25°C
• Refractive Index: 1.291
• Boiling Point: 60.36 °C at 760 mmHg
• Flash Point: -4.738 °C
• PSA: 12.53000
• Density: 1.654 g/cm³
• LogP: 1.88000

Purity/Quality:

99% ^*data from raw suppliers

2,2-bis(Trifluoromethyl)oxirane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 10
• Safety Statements: 16

MSDS Files:

SDS file from LookChem

Useful:

• Use Description: 2,2-Bis(trifluoromethyl)oxirane, also known as bis(trifluoromethyl)ethylene oxide, has several important applications across various fields. In the field of organic synthesis, it serves as a versatile building block for the creation of complex organic molecules. Its trifluoromethyl groups can be selectively modified to introduce desired chemical functionalities, making it valuable for drug discovery and the synthesis of specialty chemicals. In the realm of materials science, this compound can be used as a monomer in the preparation of specialty polymers and materials with unique properties, including high thermal stability and resistance to chemical degradation. Additionally, in the field of fluorine chemistry, it contributes to the development of novel fluorinated compounds with potential applications in pharmaceuticals, agrochemicals, and materials. Its multifaceted utility underscores its significance in advancing organic chemistry, materials science, and the discovery of new molecules with diverse applications.

Technology Process of 2,2-Bis(trifluoromethyl)oxirane

There total 5 articles about 2,2-Bis(trifluoromethyl)oxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

hexafluoroisobutylene (1027143-59-4) → 2,2-bis(trifluoromethyl)oxirane (31898-68-7)

Guidance literature:

With sodium hypochlorite; Aliquat 336; at -5 - 2 ℃; for 1.5 - 2h;

Reference yield: 75.0%

2-trifluoromethyl-3,3,3-trifluoropropene (382-10-5) → 2,2-bis(trifluoromethyl)oxirane (31898-68-7)

Guidance literature:

With sodium hypochlorite; Aliquat 336; at -2 - 2 ℃; for 2h;

DOI:10.1016/j.jfluchem.2003.11.002

Reference yield:

2-trifluoromethyl-3,3,3-trifluoropropene (382-10-5) → 2,2-bis(trifluoromethyl)oxirane (31898-68-7) + Hexafluoroacetone (684-16-2)

Guidance literature:

With oxygen; at 230 ℃; for 12h; under 10343.2 Torr; Product distribution / selectivity;

upstream raw materials:

diazomethane

Hexafluoroacetone

2-trifluoromethyl-3,3,3-trifluoropropene

hexafluoroisobutylene

Downstream raw materials:

2-benzyl-1,1,1,3,3,3-hexafluoro-2-propanol

1,1,4,4-tetrakis(trifluoromethyl)butane-1,4-diol

1,1-bis(trifluoromethyl)-2-bromoethanol

2-[(diphenylphosphanyl)methyl]-1,1,1,3,3,3-hexafluoro-propan-2-ol

Refernces

• 1、 Petrov, Viacheslav A.. "Reactions of 2,2-bis(trifluoromethyl)oxirane with alcohols under phase transfer catalysis". . p. 531 - 536. Retrieved 2004.
• 2、 Chi,Ranjan,Chou,Liu,Peng,Lee. "Preparation and characterization of volatile alkaline-earth metal complexes with multiply coordinated aminoalkoxide ligands". . p. 2462 - 2466. Retrieved 2001.
• 3、 -. "PROCESS FOR PREPARING HEXAFLUOROISOBUTENE EPOXIDE". Page/Page column 1-2. . Retrieved 2008/12/07.