4-CHLORO-1,1,1-TRIFLUOROBUTANE

Base Information

• Chemical Name: 4-CHLORO-1,1,1-TRIFLUOROBUTANE
• CAS No.: 406-85-9
• Molecular Formula: C₄H₆ClF₃
• Molecular Weight: 146.54
• Hs Code.: 2903793090
• Mol file: 406-85-9.mol

Synonyms:4,4,4-Trifluorobutylchloride; 4-Chloro-1,1,1-trifluorobutane; HCFC 373mff

Chemical Property of 4-CHLORO-1,1,1-TRIFLUOROBUTANE

Chemical Property:

• Vapor Pressure: 109mmHg at 25°C
• Melting Point: -67.25
• Refractive Index: 1.3505
• Boiling Point: 81
• Flash Point: 10.8°C
• PSA: 0.00000
• Density: 1.2425
• LogP: 2.56770

Purity/Quality:

98%Min ^*data from raw suppliers

4-Chloro-1,1,1-trifluorobutane ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F

MSDS Files:

Useful:

Technology Process of 4-CHLORO-1,1,1-TRIFLUOROBUTANE

There total 6 articles about 4-CHLORO-1,1,1-TRIFLUOROBUTANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

1-iodo-3-chloro-propane (6940-76-7) + (trifluoromethyl)trimethylsilane (81290-20-2) → 1-chloro-4,4,4-trifluorobutane (406-85-9)

Guidance literature:

With 15-crown-5; cesium fluoride; In diethyl ether; at -18 - 20 ℃; for 1h;

DOI:10.1016/j.jfluchem.2007.02.017

Reference yield:

1,1,1-trifluorobutane (460-34-4) → 3-chloro-1,1,1-trifluoro-butane (406-50-8) + 1-chloro-4,4,4-trifluorobutane (406-85-9)

Guidance literature:

With water; beim Chlorieren im Sonnenlicht;

Reference yield:

γ-chlorobutyric acid (627-00-9) → 1-chloro-4,4,4-trifluorobutane (406-85-9)

Guidance literature:

With sulfur tetrafluoride;

upstream raw materials:

1,1,1-trifluorobutane

γ-chlorobutyric acid

water

1-iodo-3-chloro-propane

Downstream raw materials:

4,4,4-trifluorobutene

Refernces