[2-(1-methylethenyl)phenyl]methyl alcohol

Base Information

• Chemical Name: [2-(1-methylethenyl)phenyl]methyl alcohol
• CAS No.: 180092-32-4
• Molecular Formula: C₁₀H₁₂O
• Molecular Weight: 148.205
• Mol file: 180092-32-4.mol

Synonyms:[2-(1-methylethenyl)phenyl]methyl alcohol

Chemical Property of [2-(1-methylethenyl)phenyl]methyl alcohol

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [2-(1-methylethenyl)phenyl]methyl alcohol

There total 13 articles about [2-(1-methylethenyl)phenyl]methyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2-(1-methylethenyl)benzaldehyde (23417-79-0) → [2-(1-methylethenyl)phenyl]methyl alcohol (180092-32-4)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 ℃; for 0.0833333h;

DOI:10.3987/COM-17-13803

Reference yield: 66.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 1-bromo-2-isopropenylbenzene (7073-70-3) → [2-(1-methylethenyl)phenyl]methyl alcohol (180092-32-4)

Guidance literature:

1-bromo-2-isopropenylbenzene; With magnesium; In diethyl ether; at 40 ℃;

formaldehyd; In diethyl ether; at 170 - 180 ℃;

DOI:10.1134/S1070428016060075

Reference yield:

2-(1-Methylethenyl)benzoesaeure-methylester (62291-44-5) → [2-(1-methylethenyl)phenyl]methyl alcohol (180092-32-4)

Guidance literature:

With diisobutylaluminium hydride; In tetrahydrofuran; hexane; at -60 - 20 ℃; for 2h; Inert atmosphere;

DOI:10.1021/acs.orglett.9b02199

upstream raw materials:

2-(2-chlorophenyl)propan-2-ol

ethyl 2-chlorobenzoate

2-bromobenzoic acid ethyl ester

formaldehyd

Downstream raw materials:

1-(chloromethyl)-2-(prop-1-en-2-yl)benzene

(2-isopropylphenyl)methanol

o-1-menthene

o-2-menthene

Refernces

• 1、 Zheng, Purui,Han, Xiaoyu,Hu, Jiao,Zhao, Xiaoming,Xu, Tao. "Enantioselective Copper-Catalyzed Desymmetrization of 1,3-Diketones Involving Borylation of Styrenes". . p. 6040 - 6044. Retrieved 2019/08/27.
• 2、 -. "C- ARYL GLYCOSID DERIVATIVES, PHARMACEUTICAL COMPOSITION, PREPARATION PROCESS AND USES THEREOF". . . Retrieved 2017/04/19.