3-Oxybenz-4-chloranilid

Base Information

• Chemical Name: 3-Oxybenz-4-chloranilid
• CAS No.: 73544-82-8
• Molecular Formula: C₁₃H₁₀ClNO₂
• Molecular Weight: 247.681
• Mol file: 73544-82-8.mol

Synonyms:3-Oxybenz-4-chloranilid

Chemical Property of 3-Oxybenz-4-chloranilid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Oxybenz-4-chloranilid

There total 2 articles about 3-Oxybenz-4-chloranilid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-chloro-aniline (106-47-8) + 3-Carboxyphenol (99-06-9) → 3-Oxybenz-4-chloranilid (73544-82-8)

Guidance literature:

3-Carboxyphenol; With oxalyl dichloride; In tetrahydrofuran; at 0 ℃; for 1.5h;

4-chloro-aniline; With hydrogenchloride; In tetrahydrofuran; for 3h;

DOI:10.3390/molecules21050612

Reference yield:

→ 3-Oxybenz-4-chloranilid (73544-82-8)

Guidance literature:

3-Oxybenzoylchlorid, 4-Chloranilin;

Reference yield: 89.0%

3-Oxybenz-4-chloranilid (73544-82-8) + 6,7-dimethoxy-4-chloroquinazoline (13790-39-1) → N-(4-chlorophenyl)-3-((6,7-dimethoxyquinazolin-4-yl)oxy)benzamide

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 24h;

DOI:10.3390/molecules21050612

upstream raw materials:

4-chloro-aniline

3-Carboxyphenol

Refernces

• 1、 SCHOENENBERGER,HOLZHEU-ECKARDT,BAMANN. "COMPARATIVE STUDIES ON THE PREPARATION OF ISOMERIC HYDROXYBENZAMIDES.". . p. 324 - 328. Retrieved 2007/10/05.