Cyclohexanecarboxylic acid, 1-amino-4-methoxy-, trans- (9CI)

Base Information

• Chemical Name: Cyclohexanecarboxylic acid, 1-amino-4-methoxy-, trans- (9CI)
• CAS No.: 387825-55-0
• Molecular Formula: C₈H₁₅NO₃
• Molecular Weight: 173.212
• Mol file: 387825-55-0.mol

Synonyms:Cyclohexanecarboxylic acid, 1-amino-4-methoxy-, trans- (9CI)

Chemical Property of Cyclohexanecarboxylic acid, 1-amino-4-methoxy-, trans- (9CI)

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of Cyclohexanecarboxylic acid, 1-amino-4-methoxy-, trans- (9CI)

There total 8 articles about Cyclohexanecarboxylic acid, 1-amino-4-methoxy-, trans- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

cis-8-methoxy-1,3-diazaspiro[4,5]-decane-2,4-dione (387825-48-1) → cis-1-amino-4-methoxycyclohexane-1-carboxylic acid (387825-55-0)

Guidance literature:

With barium(II) hydroxide; In water; at 40 ℃; for 45h;

Reference yield: 92.0%

cis-8-methoxy-1,3-diazaspiro[4.5]decane-2,4-dione (387825-48-1) → cis-1-amino-4-methoxycyclohexane-1-carboxylic acid (387825-55-0)

Guidance literature:

With water; calcium hydroxide; at 95 ℃; for 45h;

DOI:10.1134/S1070428020100176

Reference yield:

4-methoxycyclohexanone (13482-23-0) + ammonium cyanide (629653-39-0) → cis-1-amino-4-methoxycyclohexane-1-carboxylic acid (387825-55-0)

Guidance literature:

4-methoxycyclohexanone; ammonium cyanide; With cetyltributylphosphonium bromide; In water; butan-1-ol; at 0 - 30 ℃; for 14h;

With water; calcium hydroxide; at 0 - 90 ℃; for 5h;

upstream raw materials:

4-methoxy-aniline

1-amino-4-methoxycyclohexane

cis-8-methoxy-1,3-diazaspiro[4,5]-decane-2,4-dione

4-methoxy-phenol

Refernces

• 1、 Mao, Longfei,Wang, Jiahao,Xu, Guiqing,Zhou, Yingjie. "A High-Yield and Cost-Effective Synthesis of Spirotetramat". . p. 1775 - 1778. Retrieved 2020/12/01.
• 2、 -. "Novel spirodecenol compound and preparation method thereof". . . Retrieved 2018/05/16.