Technology Process of 3β-((dimethylphenylsilyl)oxy)-6-methylene-5α-androstan-17-one
There total 5 articles about 3β-((dimethylphenylsilyl)oxy)-6-methylene-5α-androstan-17-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 42.4 percent / p-TsOH / 0.08 h / Heating
2: 93 percent / potassium tert-butoxide / tetrahydrofuran / Ambient temperature
3: CrO3, H2SO4 / acetone / 1 h / 20 °C
4: lithium tri-tert-butoxyaluminohydride / tetrahydrofuran / -78 °C
5: 1.3 g / triethylamine / dimethylformamide / 2.5 h
With
chromium(VI) oxide; lithium tri(t-butoxy)aluminum hydride; sulfuric acid; potassium tert-butylate; toluene-4-sulfonic acid; triethylamine;
In
tetrahydrofuran; N,N-dimethyl-formamide; acetone;
DOI:10.1021/ja9808595
- Guidance literature:
-
Multi-step reaction with 2 steps
1: lithium tri-tert-butoxyaluminohydride / tetrahydrofuran / -78 °C
2: 1.3 g / triethylamine / dimethylformamide / 2.5 h
With
lithium tri(t-butoxy)aluminum hydride; triethylamine;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/ja9808595
- Guidance literature:
-
Multi-step reaction with 3 steps
1: CrO3, H2SO4 / acetone / 1 h / 20 °C
2: lithium tri-tert-butoxyaluminohydride / tetrahydrofuran / -78 °C
3: 1.3 g / triethylamine / dimethylformamide / 2.5 h
With
chromium(VI) oxide; lithium tri(t-butoxy)aluminum hydride; sulfuric acid; triethylamine;
In
tetrahydrofuran; N,N-dimethyl-formamide; acetone;
DOI:10.1021/ja9808595