2-(BENZYLOXY)-ETHYLAMINE

Base Information

• Chemical Name: 2-(BENZYLOXY)-ETHYLAMINE
• CAS No.: 38336-04-8
• Molecular Formula: C9H13NO
• Molecular Weight: 151.208
• Hs Code.: 2922199090
• Mol file: 38336-04-8.mol

Synonyms:Ethylamine,2-(benzyloxy)- (7CI);2-(Benzyloxy)ethanamine;2-(Phenylmethoxy)ethanamine;2-Aminoethyl benzyl ether;O-Benzylethanolamine;2-(Benzyloxy)ethylamine;

Chemical Property of 2-(BENZYLOXY)-ETHYLAMINE

Chemical Property:

• Refractive Index: 1.5260
• Boiling Point: 240.6 °C at 760 mmHg
• PKA: 8.82±0.10(Predicted)
• Flash Point: 84.9 °C
• PSA: 35.25000
• Density: 1.016 g/cm³
• LogP: 1.86220
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility.: Chloroform (Slightly), DMSO (Slightly)

Purity/Quality:

98%, ^*data from raw suppliers

2-(Benzyloxy)ethanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(BENZYLOXY)-ETHYLAMINE

There total 19 articles about 2-(BENZYLOXY)-ETHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

→ O-benzylethanolamine (38336-04-8)

Guidance literature:

With water; potassium hydroxide; In ethanol; at 90 ℃; for 10h;

Reference yield: 94.5%

benzyl chloride (100-44-7) + ethanolamine (141-43-5) → O-benzylethanolamine (38336-04-8)

Guidance literature:

With sodium carbonate; at 60 - 95 ℃; Reagent/catalyst; Temperature;

Reference yield: 93.0%

((2-azidoethoxy)methyl)benzene (66021-75-8) → O-benzylethanolamine (38336-04-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; ethylenediamine; In methanol; at 20 ℃; for 6h;

DOI:10.1021/jo9814694

upstream raw materials:

ethyleneimine

benzyl alcohol

((2-azidoethoxy)methyl)benzene

benzyl chloride

Downstream raw materials:

N-(2-benzyloxy-ethyl)-N'-(2-chloro-ethyl)-phosphorodiamidic acid but-3-enyl ester

[1-(2-Benzyloxy-ethylcarbamoyl)-3-hydroxy-propyl]-carbamic acid benzyl ester

N-(2-Benzyloxy-ethyl)-2-dibenzylamino-4-hydroxy-butyramide

2-Benzamido-N-(2-benzyloxyaethyl)-4-hydroxybutyramid

Refernces

• 1、 Ashley, Melissa A.,Yamauchi, Chiaki,Chu, John C. K.,Otsuka, Shinya,Yorimitsu, Hideki,Rovis, Tomislav. "Photoredox-Catalyzed Site-Selective α-C(sp3)?H Alkylation of Primary Amine Derivatives". supporting information. p. 4002 - 4006. Retrieved 2019/02/24.
• 2、 -. "A method for the production of primary amines". Paragraph 0237; 0307. . Retrieved 2016/10/09.