4-(2,4-Dihydroxyphenyl)butylamidino-3,5-diamino-6-chloropyrazine carboxamide hydrochloride

Base Information

• Chemical Name: 4-(2,4-Dihydroxyphenyl)butylamidino-3,5-diamino-6-chloropyrazine carboxamide hydrochloride
• CAS No.: 583825-26-7
• Molecular Formula: C₁₆H₂₀ClN₇O₃*ClH
• Molecular Weight: 430.294
• Mol file: 583825-26-7.mol

Synonyms:4-(2,4-Dihydroxyphenyl)butylamidino-3,5-diamino-6-chloropyrazine carboxamide hydrochloride

Chemical Property of 4-(2,4-Dihydroxyphenyl)butylamidino-3,5-diamino-6-chloropyrazine carboxamide hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(2,4-Dihydroxyphenyl)butylamidino-3,5-diamino-6-chloropyrazine carboxamide hydrochloride

There total 6 articles about 4-(2,4-Dihydroxyphenyl)butylamidino-3,5-diamino-6-chloropyrazine carboxamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

4-(2,4-Dimethoxyphenyl)butylamidino-3,5-diamino-6-chloropyrazine carboxamide hydrochloride → 4-(2,4-Dihydroxyphenyl)butylamidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride + 4-(2,4-Dihydroxyphenyl)butylamidino-3,5-diamino-6-chloropyrazine carboxamide hydrochloride (583825-26-7)

Guidance literature:

With hydrogenchloride; In hydrogen bromide;

Reference yield:

4-(2,4-Dimethoxyphenyl)butyl amine (583825-37-0) → 4-(2,4-Dihydroxyphenyl)butylamidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride + 4-(2,4-Dihydroxyphenyl)butylamidino-3,5-diamino-6-chloropyrazine carboxamide hydrochloride (583825-26-7)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride

2: hydrogenchloride / hydrogen bromide

With hydrogenchloride; In hydrogen bromide;

Reference yield:

4-(2,4-dimethoxy-phenyl)-butan-1-ol (107153-52-6) → 4-(2,4-Dihydroxyphenyl)butylamidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride + 4-(2,4-Dihydroxyphenyl)butylamidino-3,5-diamino-6-chloropyrazine carboxamide hydrochloride (583825-26-7)

Guidance literature:

Multi-step reaction with 5 steps

1: triethylamine

3: LiAlH₄ / tetrahydrofuran

4: hydrogenchloride

5: hydrogenchloride / hydrogen bromide

With hydrogenchloride; LiAlH₄; triethylamine; In tetrahydrofuran; hydrogen bromide;

upstream raw materials:

4-(2,4-Dimethoxyphenyl)butyl azide

methanesulfonic acid 4-(2,4-dimethoxyphenyl)butyl ester

4-(2,4-Dimethoxyphenyl)butyl amine

4-(2,4-dimethoxy-phenyl)-butan-1-ol

Refernces