3,3-bis(4-(trifluoromethylsulfonyloxy)phenyl)-1(3H)-isobenzofuranone

Base Information

• Chemical Name: 3,3-bis(4-(trifluoromethylsulfonyloxy)phenyl)-1(3H)-isobenzofuranone
• CAS No.: 1140964-66-4
• Molecular Formula: C₂₂H₁₂F₆O₈S₂
• Molecular Weight: 582.455
• Mol file: 1140964-66-4.mol

Synonyms:3,3-bis(4-(trifluoromethylsulfonyloxy)phenyl)-1(3H)-isobenzofuranone

Chemical Property of 3,3-bis(4-(trifluoromethylsulfonyloxy)phenyl)-1(3H)-isobenzofuranone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,3-bis(4-(trifluoromethylsulfonyloxy)phenyl)-1(3H)-isobenzofuranone

There total 1 articles about 3,3-bis(4-(trifluoromethylsulfonyloxy)phenyl)-1(3H)-isobenzofuranone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trifluoromethylsulfonic anhydride (358-23-6) + phenolphthalein (77-09-8) → 3,3-bis(4-(trifluoromethylsulfonyloxy)phenyl)-1(3H)-isobenzofuranone (1140964-66-4)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃; for 1.5h; Inert atmosphere;

DOI:10.1016/j.tet.2009.01.033

Reference yield: 45.0%

(2-furyl)methyl alcohol (98-00-0,25212-86-6,93793-62-5) + 3,3-bis(4-(trifluoromethylsulfonyloxy)phenyl)-1(3H)-isobenzofuranone (1140964-66-4) → 3,3-bis(4-(furan-2-ylmethyl)phenyl)isobenzofuran-1(3H)-one

Guidance literature:

With Dimethyl oxalate; 1,1'-bis-(diphenylphosphino)ferrocene; manganese; 1,10-Phenanthroline; [1,1'-bis(diphenylphosphino)ferrocene]nickel(II) chloride; In N,N-dimethyl-formamide; at 80 ℃; for 30h; chemoselective reaction; Inert atmosphere; Sealed tube;

DOI:10.1021/jacs.0c12462

Reference yield: 44.0%

3,3-bis(4-(trifluoromethylsulfonyloxy)phenyl)-1(3H)-isobenzofuranone (1140964-66-4) → 3,3-bis(4-aminophenyl)isobenzofuran-1-(3H)-one (509-77-3)

Guidance literature:

With dichlorobis(tri-O-tolylphosphine)palladium; nicotinamide; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; at 150 ℃; for 16h; Inert atmosphere;

DOI:10.1016/j.tet.2009.01.033

upstream raw materials:

trifluoromethylsulfonic anhydride

phenolphthalein

Downstream raw materials:

3,3-bis(4-aminophenyl)isobenzofuran-1-(3H)-one

Refernces

• 1、 Romero,Harrak,Basset,Orúe,Pujol. "Direct synthesis of primary arylamines via C-N cross-coupling of aryl bromides and triflates with amides". experimental part. p. 1951 - 1956. Retrieved 2009/07/11.