5-Tosyloxy-2,2-ethylenedioxypentane

Base Information

• Chemical Name: 5-Tosyloxy-2,2-ethylenedioxypentane
• CAS No.: 41913-82-0
• Molecular Formula: C₁₄H₂₀O₅S
• Molecular Weight: 300.376
• Mol file: 41913-82-0.mol

Synonyms:5-Tosyloxy-2,2-ethylenedioxypentane

Chemical Property of 5-Tosyloxy-2,2-ethylenedioxypentane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-Tosyloxy-2,2-ethylenedioxypentane

There total 6 articles about 5-Tosyloxy-2,2-ethylenedioxypentane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(2-methyl-[1,3]dioxolan-2-yl)-propan-1-ol (29021-98-5) + p-toluenesulfonyl chloride (98-59-9) → 5-Tosyloxy-2,2-ethylenedioxypentane (41913-82-0)

Guidance literature:

With pyridine; at 0 ℃;

Reference yield:

Ethyl levulinate ethylene ketal (941-43-5) → 5-Tosyloxy-2,2-ethylenedioxypentane (41913-82-0)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄ / tetrahydrofuran / Ambient temperature

2: pyridine / 18 h / Ambient temperature

With pyridine; lithium aluminium tetrahydride; In tetrahydrofuran;

DOI:10.1021/jm980469t

Reference yield:

4-oxopentanoic acid ethyl ester (539-88-8) → 5-Tosyloxy-2,2-ethylenedioxypentane (41913-82-0)

Guidance literature:

Multi-step reaction with 3 steps

1: p-toluenesulfonic acid / benzene / 2 h / Heating

2: LiAlH₄ / tetrahydrofuran / Ambient temperature

3: pyridine / 18 h / Ambient temperature

With pyridine; lithium aluminium tetrahydride; toluene-4-sulfonic acid; In tetrahydrofuran; benzene;

DOI:10.1021/jm980469t

upstream raw materials:

3-(2-methyl-[1,3]dioxolan-2-yl)-propan-1-ol

p-toluenesulfonyl chloride

1-acetoxy-3-(2-methyl-[1,3]dioxolan-2-yl)-propane

4-oxopentyl acetate

Refernces

• 1、 Umemura, Kazuyuki,Watanabe, Koichi,Ono, Kazumasa,Yamaura, Masanori,Yoshimura, Juji. "Total synthesis of antibiotic karnamicin B1". . p. 4811 - 4814. Retrieved 2007/10/03.
• 2、 Odinokov, V. N.,Kukovinets, O. S.,Zainullin, R. A.,Ishmuratov, G. Yu.,Isakova, L. A.,Tolstikov, G. A.. "OZONOLYSIS OF ALKENES AND REACTIONS OF POLYFUNCTIONAL COMPOUNDS. XXXII. SYNTHESIS OF (ξ)-3,7-DIMETHYL-2,7-OCTADIENYL PROPIONATE". . p. 2017 - 2021. Retrieved 2007/10/02.