Methyl 2,4-Dichlorophenylacetate

Base Information

• Chemical Name: Methyl 2,4-Dichlorophenylacetate
• CAS No.: 55954-23-9
• Molecular Formula: C9H8Cl2O2
• Molecular Weight: 219.067
• Hs Code.: 29163900
• European Community (EC) Number: 611-334-7
• DSSTox Substance ID: DTXSID50370129
• Nikkaji Number: J2.171.083K
• Wikidata: Q72490038
• Mol file: 55954-23-9.mol

Synonyms:Methyl 2,4-Dichlorophenylacetate;55954-23-9;methyl 2-(2,4-dichlorophenyl)acetate;2,4-Dichlorophenylacetic acid methyl ester;Benzeneacetic acid, 2,4-dichloro-, methyl ester;Methyl2,4-dichlorophenylacetate;DCAA methyl ester;2,4-DCAA methyl ester;SCHEMBL837451;DTXSID50370129;methyl 2,4-dichlorobenzeneacetate;MFCD00018381;AKOS015849924;AC-3030;CS-W005710;AS-12649;2,4-dichlorobenzeneacetic acid methyl ester;FT-0640351;M2528;(2,4-dichloro-phenyl)acetic acid methyl ester;O11846

Chemical Property of Methyl 2,4-Dichlorophenylacetate

Chemical Property:

• Appearance/Colour: clear colorless to yellow liquid
• Vapor Pressure: 0.00613mmHg at 25°C
• Refractive Index: 1.539-1.542
• Boiling Point: 272.3 °C at 760 mmHg
• Flash Point: 111.5 °C
• PSA: 26.30000
• Density: 1.318 g/cm³
• LogP: 2.70890
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 217.9901349
• Heavy Atom Count: 13
• Complexity: 185

Purity/Quality:

98%,99%, ^*data from raw suppliers

Methyl 2,4-Dichlorophenylacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi,Xn,N,F
• Hazard Codes: Xi,Xn,N,F
• Statements: 22-67-65-62-51/53-48/20-38-11-66-36/38-36
• Safety Statements: 24/25-62-61-36/37-33-29-16-9-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC(=O)CC1=C(C=C(C=C1)Cl)Cl

Technology Process of Methyl 2,4-Dichlorophenylacetate

There total 3 articles about Methyl 2,4-Dichlorophenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + 2,4-dichlorophenylacetic acid (19719-28-9) → methyl 2-(2,4-dichlorophenyl)acetate (55954-23-9)

Guidance literature:

With hydrogenchloride; for 1h; Heating;

DOI:10.1016/S0968-0896(03)00220-7

Reference yield: 100.0%

2,4-dichlorophenylacetic acid (19719-28-9) + methyl iodide (74-88-4) → methyl 2-(2,4-dichlorophenyl)acetate (55954-23-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 21h;

Reference yield: 99.0%

→ methyl 2-(2,4-dichlorophenyl)acetate (55954-23-9)

Guidance literature:

upstream raw materials:

methanol

2,4-dichlorophenylacetic acid

methyl iodide

Downstream raw materials:

2,4-Dichlorphenylacetylguanidin

methyl 2-(2,4-dichlorophenyl)pent-4-enoate

Methyl 2-diazo-2-(2,4-dichlorophenyl)acetate

3-(2,4-Dichloro-phenyl)-4-hydroxy-6-methyl-1H-pyridin-2-one

Refernces

• 1、 Bao, Longzhu,Wang, Shuangshuang,Song, Di,Wang, Jingjing,Cao, Xiufang,Ke, Shaoyong. "Synthesis and bio-evaluation of natural butenolides-acrylate conjugates". . . Retrieved 2019/04/05.
• 2、 -. "COMPOSITIONS USEFUL FOR TREATING DISORDERS RELATED TO KIT". Paragraph 0195-0196. . Retrieved 2016/04/26.