3-(benzhydrylthio)propanamide

Base Information

• Chemical Name: 3-(benzhydrylthio)propanamide
• CAS No.: 135468-50-7
• Molecular Formula: C₁₆H₁₇NOS
• Molecular Weight: 271.383
• Mol file: 135468-50-7.mol

Synonyms:3-(benzhydrylthio)propanamide

Chemical Property of 3-(benzhydrylthio)propanamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(benzhydrylthio)propanamide

There total 3 articles about 3-(benzhydrylthio)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-Benzhydrylsulfanyl-propionyl chloride → 3-(benzhydrylthio)propanamide (135468-50-7)

Guidance literature:

With ammonia; In dichloromethane; at 0 ℃; Yield given;

DOI:10.1021/ja00016a031

Reference yield:

1,1-Diphenylmethanol (91-01-0) → 3-(benzhydrylthio)propanamide (135468-50-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent / trifluoroacetic acid / 0.25 h

2: oxalyl chloride / Heating

3: NH₃ / CH₂Cl₂ / 0 °C

With oxalyl dichloride; ammonia; In dichloromethane; trifluoroacetic acid;

DOI:10.1021/ja00016a031

Reference yield:

3-(benzhydrylthio)propanoic acid (63547-34-2) → 3-(benzhydrylthio)propanamide (135468-50-7)

Guidance literature:

Multi-step reaction with 2 steps

1: oxalyl chloride / Heating

2: NH₃ / CH₂Cl₂ / 0 °C

With oxalyl dichloride; ammonia; In dichloromethane;

DOI:10.1021/ja00016a031

upstream raw materials:

1,1-Diphenylmethanol

3-(benzhydrylthio)propanoic acid

Downstream raw materials:

3,3'-disulfanediylpropanamide

Refernces