Technology Process of (SS,RR)-monocyclofarnesal N-methylnitrone
There total 5 articles about (SS,RR)-monocyclofarnesal N-methylnitrone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium methylate;
In
ethanol;
at 25 ℃;
for 18h;
DOI:10.1021/jo00209a003
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 68 percent / water, NBS / tetrahydrofuran / 4 h / 25 °C
2: 85percent phosphoric acid / hexane / 6 h / 25 °C
3: 1.) zinc, glacial AcOH, 2.) LiAlH4 / 1.) ether, reflux, 18 h, 2.) THF, reflux, 17 h
4: 81 percent / pyridine, CrO3 / CH2Cl2 / 1.5 h / 25 °C
5: 76 percent / sodium methoxide / ethanol / 18 h / 25 °C
With
pyridine; chromium(VI) oxide; N-Bromosuccinimide; lithium aluminium tetrahydride; phosphoric acid; water; sodium methylate; acetic acid; zinc;
In
tetrahydrofuran; ethanol; hexane; dichloromethane;
DOI:10.1021/jo00209a003
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 85percent phosphoric acid / hexane / 6 h / 25 °C
2: 1.) zinc, glacial AcOH, 2.) LiAlH4 / 1.) ether, reflux, 18 h, 2.) THF, reflux, 17 h
3: 81 percent / pyridine, CrO3 / CH2Cl2 / 1.5 h / 25 °C
4: 76 percent / sodium methoxide / ethanol / 18 h / 25 °C
With
pyridine; chromium(VI) oxide; lithium aluminium tetrahydride; phosphoric acid; sodium methylate; acetic acid; zinc;
In
ethanol; hexane; dichloromethane;
DOI:10.1021/jo00209a003
