Technology Process of 7-[2-((Z)-3-diethylaminoprop-1-enyl)-4-fluorobenzenesulfonyl-amino]-10H-9-oxa-1,2-diazaphenanthrene-8-carboxylate
There total 11 articles about 7-[2-((Z)-3-diethylaminoprop-1-enyl)-4-fluorobenzenesulfonyl-amino]-10H-9-oxa-1,2-diazaphenanthrene-8-carboxylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: ammonium formate; palladium 10% on activated carbon / ethanol / 1 h / Reflux; Inert atmosphere
2: sulfuric acid / methanol / 16 h / Reflux
3: dichloromethane; pyridine / 96 h / 20 °C
4: tris-(dibenzylideneacetone)dipalladium(0); tri-tertiary-butyl phosphonium tetrafluoroborate / 1,4-dioxane; dimethyl sulfoxide / 2.25 h / 95 °C / Inert atmosphere
With
tris-(dibenzylideneacetone)dipalladium(0); sulfuric acid; palladium 10% on activated carbon; tri-tertiary-butyl phosphonium tetrafluoroborate; ammonium formate;
In
1,4-dioxane; pyridine; methanol; ethanol; dichloromethane; dimethyl sulfoxide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: dichloromethane; pyridine / 96 h / 20 °C
2: tris-(dibenzylideneacetone)dipalladium(0); tri-tertiary-butyl phosphonium tetrafluoroborate / 1,4-dioxane; dimethyl sulfoxide / 2.25 h / 95 °C / Inert atmosphere
With
tris-(dibenzylideneacetone)dipalladium(0); tri-tertiary-butyl phosphonium tetrafluoroborate;
In
1,4-dioxane; pyridine; dichloromethane; dimethyl sulfoxide;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: trichlorophosphate / 0.75 h / 95 °C
2: ammonium formate; palladium 10% on activated carbon / ethanol / 1 h / Reflux; Inert atmosphere
3: sulfuric acid / methanol / 16 h / Reflux
4: dichloromethane; pyridine / 96 h / 20 °C
5: tris-(dibenzylideneacetone)dipalladium(0); tri-tertiary-butyl phosphonium tetrafluoroborate / 1,4-dioxane; dimethyl sulfoxide / 2.25 h / 95 °C / Inert atmosphere
With
tris-(dibenzylideneacetone)dipalladium(0); sulfuric acid; palladium 10% on activated carbon; tri-tertiary-butyl phosphonium tetrafluoroborate; ammonium formate; trichlorophosphate;
In
1,4-dioxane; pyridine; methanol; ethanol; dichloromethane; dimethyl sulfoxide;
