3-IODOBENZHYDRAZIDE

Base Information

• Chemical Name: 3-IODOBENZHYDRAZIDE
• CAS No.: 39115-94-1
• Molecular Formula: C7H7 I N2 O
• Molecular Weight: 262.05
• Hs Code.: 2928000090
• Mol file: 39115-94-1.mol

Synonyms:(3-Iodobenzoyl)hydrazine;3-Iodobenzhydrazide; 3-Iodobenzohydrazide; 3-Iodobenzoic acid hydrazide;m-Iodobenzoic acid hydrazide; m-Iodobenzoic hydrazide

Chemical Property of 3-IODOBENZHYDRAZIDE

Chemical Property:

• Vapor Pressure: 5.83E-07mmHg at 25°C
• Melting Point: 151-153°C
• Refractive Index: 1.665
• Boiling Point: 395.4°Cat760mmHg
• PKA: 11.97±0.10(Predicted)
• Flash Point: 192.9°C
• PSA: 55.12000
• Density: 1.884g/cm³
• LogP: 1.98590
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-iodobenzohydrazide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-IODOBENZHYDRAZIDE

There total 6 articles about 3-IODOBENZHYDRAZIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,5-dioxopyrrolidin-1-yl 3-iodobenzoate (91487-18-2) → 3-iodobenzhydrazide (39115-94-1)

Guidance literature:

With hydrazine hydrate; triethylamine; In acetonitrile; at 20 ℃;

DOI:10.1016/j.tetlet.2006.07.047

Reference yield: 92.0%

methyl 3-iodo-benzoate (618-91-7) → 3-iodobenzhydrazide (39115-94-1)

Guidance literature:

With hydrazine hydrate; In ethanol; for 18h; Reflux;

Reference yield: 91.0%

→ 3-iodobenzhydrazide (39115-94-1)

Guidance literature:

upstream raw materials:

methyl 3-iodo-benzoate

3-iodobenzoic acid methyl ester

2,5-dioxopyrrolidin-1-yl 3-iodobenzoate

3-Iodobenzoic acid

Downstream raw materials:

N-3-iodobenzoyl-N'-(2,2,2-trichloroethylidene) hydrazine

Refernces

• 1、 Yuan, Chen,Yan, Jie,Song, Chen,Yang, Fan,Li, Chao,Wang, Cheng,Su, Huiling,Chen, Wei,Wang, Lijiao,Wang, Zhouyu,Qian, Shan,Yang, Lingling. "Discovery of [1,2,4]triazole derivatives as new metallo-β-lactamase inhibitors". . . Retrieved 2020/01/11.
• 2、 Xu,Wang,Luo,Yu,Guo,Fu,Zhao,Wu. "Design, synthesis, insecticidal activity and 3D-QSR study for novel trifluoromethyl pyridine derivatives containing an 1,3,4-oxadiazole moiety". . p. 6306 - 6314. Retrieved 2018/02/19.