Technology Process of 5-methoxy-7-(4-methoxyphenyl)-2,2-dimethyl-2H,6H-benzo[1,2-b:5,4-b']-dipyran-6-one
There total 16 articles about 5-methoxy-7-(4-methoxyphenyl)-2,2-dimethyl-2H,6H-benzo[1,2-b:5,4-b']-dipyran-6-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: KOH / ethanol / Heating
2: K2CO3 / dimethylformamide / 120 °C
3: 1.) thallium(III) nitrate (TTN), 2.) NaHSO3 / 1.) MeOH, 60 deg C, 2.) 0 deg C, 30 min
4: 1.) H2, 2.) 10percent HCl / 10percent Pd/C / 1.) MeOH, 2.) MeOH, reflux
5: aq. NaBH4 / tetrahydrofuran / 0.5 h / 0 °C
6: TsOH*H2O / toluene / 110 °C
7: BCl3 / CH2Cl2 / 1 h / -70 - -65 °C
8: K2CO3 / acetone / Heating
With
hydrogenchloride; potassium hydroxide; sodium tetrahydroborate; hydrogen; boron trichloride; potassium carbonate; toluene-4-sulfonic acid; sodium hydrogensulfite; thallium(III) nitrate;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol; dichloromethane; N,N-dimethyl-formamide; acetone; toluene;
DOI:10.3987/COM-91-5918
- Guidance literature:
-
Multi-step reaction with 7 steps
1: K2CO3 / dimethylformamide / 120 °C
2: 1.) thallium(III) nitrate (TTN), 2.) NaHSO3 / 1.) MeOH, 60 deg C, 2.) 0 deg C, 30 min
3: 1.) H2, 2.) 10percent HCl / 10percent Pd/C / 1.) MeOH, 2.) MeOH, reflux
4: aq. NaBH4 / tetrahydrofuran / 0.5 h / 0 °C
5: TsOH*H2O / toluene / 110 °C
6: BCl3 / CH2Cl2 / 1 h / -70 - -65 °C
7: K2CO3 / acetone / Heating
With
hydrogenchloride; sodium tetrahydroborate; hydrogen; boron trichloride; potassium carbonate; toluene-4-sulfonic acid; sodium hydrogensulfite; thallium(III) nitrate;
palladium on activated charcoal;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; acetone; toluene;
DOI:10.3987/COM-91-5918
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1.) thallium(III) nitrate (TTN), 2.) NaHSO3 / 1.) MeOH, 60 deg C, 2.) 0 deg C, 30 min
2: 1.) H2, 2.) 10percent HCl / 10percent Pd/C / 1.) MeOH, 2.) MeOH, reflux
3: aq. NaBH4 / tetrahydrofuran / 0.5 h / 0 °C
4: TsOH*H2O / toluene / 110 °C
5: BCl3 / CH2Cl2 / 1 h / -70 - -65 °C
6: K2CO3 / acetone / Heating
With
hydrogenchloride; sodium tetrahydroborate; hydrogen; boron trichloride; potassium carbonate; toluene-4-sulfonic acid; sodium hydrogensulfite; thallium(III) nitrate;
palladium on activated charcoal;
In
tetrahydrofuran; dichloromethane; acetone; toluene;
DOI:10.3987/COM-91-5918