O-propyl 4-methylbenzenecarbothioate

Base Information

• Chemical Name: O-propyl 4-methylbenzenecarbothioate
• CAS No.: 224043-70-3
• Molecular Formula: C₁₁H₁₄OS
• Molecular Weight: 194.298
• Mol file: 224043-70-3.mol

Synonyms:O-propyl 4-methylbenzenecarbothioate

Chemical Property of O-propyl 4-methylbenzenecarbothioate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-propyl 4-methylbenzenecarbothioate

There total 3 articles about O-propyl 4-methylbenzenecarbothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

<(4-methylphenylsulfinyl)(propoxycarbonyl)methylene>triphenylphosphorane (161573-78-0) → di(p-tolyl) disulfide (103-19-5) + O-propyl 4-methylbenzenecarbothioate (224043-70-3) + 4-methylphenyl but-1-enyl sulfide (81281-64-3)

Guidance literature:

at 600 ℃; under 0.001 - 0.1 Torr; Title compound not separated from byproducts;

Reference yield:

4-methylbenzenesulfinyl chloride (10439-23-3) → O-propyl 4-methylbenzenecarbothioate (224043-70-3)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / tetrahydrofuran / 12 h / 0 - 20 °C

2: 3 percent Spectr_. / 600 °C / 0 - 0.1 Torr

With triethylamine; In tetrahydrofuran;

Reference yield:

(Propoxy)thiocarbonylchlorid (2812-74-0) + para-bromotoluene (106-38-7) → O-propyl 4-methylbenzenecarbothioate (224043-70-3)

Guidance literature:

With magnesium; Yield given; Multistep reaction; 1.) THF, room temperature, 2.) THF, -78 deg C, 1 h;

DOI:10.1080/00397919908085758

upstream raw materials:

(Propoxy)thiocarbonylchlorid

para-bromotoluene

<(4-methylphenylsulfinyl)(propoxycarbonyl)methylene>triphenylphosphorane

4-methylbenzenesulfinyl chloride

Downstream raw materials:

4-methylbenzylthiol

Refernces

• 1、 Aitken, R. Alan,Armstrong, Jill M.,Drysdale, Martin J.,Ross, Fiona C.,Ryan, Bruce M.. "Flash vacuum pyrolysis of stabilised phosphorus ylides. Part 15. Generation of alkoxycarbonyl(sulfenyl)carbenes and their intramolecular insertion to give alkenyl sulfides". . p. 593 - 604. Retrieved 2007/10/03.