ergosta-5,7,22-trien-3β-ol

Base Information

• Chemical Name: ergosta-5,7,22-trien-3β-ol
• CAS No.: 70005-45-7
• Molecular Formula: C₂₈H₄₄O
• Molecular Weight: 396.657
• Mol file: 70005-45-7.mol

Synonyms:ergosta-5,7,22-trien-3β-ol

Chemical Property of ergosta-5,7,22-trien-3β-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ergosta-5,7,22-trien-3β-ol

There total 14 articles about ergosta-5,7,22-trien-3β-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

C38H50N2O4 (41238-09-9,56192-94-0) → ergosta-5,7,22-triene-3β-ol (57-87-4,128-27-8,474-69-1,474-70-4,6538-06-3,7056-23-7,57760-53-9,60018-27-1,70005-45-7,82863-18-1,122565-01-9)

Guidance literature:

With sodium bis(2-methoxyethoxy)aluminium dihydride; In toluene; benzene; for 1h; Heating;

Reference yield: 75.0%

3-acetoxy-3,5,7,22-ergosta-tetraene (6411-40-1) → ergosta-5,7,22-triene-3β-ol (57-87-4,128-27-8,474-69-1,474-70-4,6538-06-3,7056-23-7,57760-53-9,60018-27-1,70005-45-7,82863-18-1,122565-01-9)

Guidance literature:

With sodium tetrahydroborate; ethanol; calcium chloride; In dichloromethane; at 20 - 35 ℃; for 3.33333h;

Reference yield:

C36H50N2O2 (81126-48-9) → ergosta-5,7,22-triene-3β-ol (57-87-4,128-27-8,474-69-1,474-70-4,6538-06-3,7056-23-7,57760-53-9,60018-27-1,70005-45-7,82863-18-1,122565-01-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 88 percent / 0.3 h / 145 - 155 °C / 2.3 Torr

2: 91 percent / lead tetraacetate / CHCl₃; methanol; acetic acid / 0.5 h

3: 78 percent / sodium bis(2-methoxyethoxy)dihydroaluminate / benzene; toluene / 1 h / Heating

With lead(IV) acetate; sodium bis(2-methoxyethoxy)aluminium dihydride; In methanol; chloroform; acetic acid; toluene; benzene;

upstream raw materials:

C₃₈H₅₀N₂O₄

C₄₃H₅₄N₂O₃

C₃₆H₅₀N₂O₂

C₃₆H₄₈N₂O₃

Downstream raw materials:

previtamin D₂

tachysterol

toxisterol₂ D

toxisterol₂ I₂

Refernces

• 1、 Orlov, A. I.,Mikhailova, N. P.,Kosarev, A. A.,Vyunov, K. A.. "PREPARATION OF ANTIRACHITIC COMPOUNDS. I. KINETIC MODEL OF THE PHOTOISOMERIZATION PROCESS OF PROVITAMIN D2". . p. 829 - 834. Retrieved 2007/10/02.