ramipril tris(hydroxymethyl)aminomethane salt

Base Information

• Chemical Name: ramipril tris(hydroxymethyl)aminomethane salt
• CAS No.: 1187092-62-1
• Molecular Formula: C₄H₁₁NO₃*C₂₃H₃₂N₂O₅
• Molecular Weight: 537.654
• Mol file: 1187092-62-1.mol

Synonyms:ramipril tris(hydroxymethyl)aminomethane salt

Chemical Property of ramipril tris(hydroxymethyl)aminomethane salt

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of ramipril tris(hydroxymethyl)aminomethane salt

There total 2 articles about ramipril tris(hydroxymethyl)aminomethane salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

Ramipril (87333-19-5,104195-90-6,1246253-05-3) + 2-amino-2-hydroxymethyl-1,3-propanediol (77-86-1) → ramipril tris(hydroxymethyl)aminomethane salt (1187092-62-1)

Guidance literature:

In ethanol; water; at 20 - 40 ℃;

Reference yield:

2--L-alanyl>-(1S,3S,5S)-2-azabicyclo<3.3.0>octane-3-carboxylic acid benzylester (87269-88-3,1356847-95-4,1356352-52-7) + 2-amino-2-hydroxymethyl-1,3-propanediol (77-86-1) → ramipril tris(hydroxymethyl)aminomethane salt (1187092-62-1)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In ethanol; water; at 20 - 30 ℃; for 2h; under 2068.65 - 3102.97 Torr;

upstream raw materials:

Ramipril

2-amino-2-hydroxymethyl-1,3-propanediol

2--L-alanyl>-(1S,3S,5S)-2-azabicyclo<3.3.0>octane-3-carboxylic acid benzylester

Refernces