1-Amino-cyclobutanecarboxylic acid ethyl ester

Base Information

• Chemical Name: 1-Amino-cyclobutanecarboxylic acid ethyl ester
• CAS No.: 285570-26-5
• Molecular Formula: C₇H₁₃NO₂
• Molecular Weight: 143.186
• Hs Code.: 2922499990
• DSSTox Substance ID: DTXSID70466432
• Nikkaji Number: J2.033.991H
• Wikidata: Q82292996
• Mol file: 285570-26-5.mol

Synonyms:285570-26-5;Ethyl 1-aminocyclobutanecarboxylate;1-Amino-cyclobutanecarboxylic acid ethyl ester;Ethyl 1-aminocyclobutane-1-carboxylate;Cyclobutanecarboxylic acid, 1-amino-, ethyl ester;1-AMINocycloBUTANECARBOXYLIC ACID ethyl ESTER;SCHEMBL571438;ethyl1-aminocyclobutanecarboxylate;DTXSID70466432;SOJJLUOGEIHGRZ-UHFFFAOYSA-N;MFCD06797199;AKOS011676028;CS-0450504;FT-0654117;EN300-314048;A819487;1-Amino-;1-Amino-cyclobutanecarboxylic acid ethyl ester (H-Ac4c-OEt)

Chemical Property of 1-Amino-cyclobutanecarboxylic acid ethyl ester

Chemical Property:

• PSA: 52.32000
• LogP: 1.13120
• Storage Temp.: 2-8°C
• XLogP3: 0.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 143.094628657
• Heavy Atom Count: 10
• Complexity: 141

Purity/Quality:

99% ^*data from raw suppliers

Ethyl1-aminocyclobutanecarboxylate 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C1(CCC1)N

Technology Process of 1-Amino-cyclobutanecarboxylic acid ethyl ester

There total 1 articles about 1-Amino-cyclobutanecarboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

ethyl 1-cyano-1-cyclobutanecarboxylate (28246-87-9) → ethyl 1-aminocyclobutanecarboxylate (285570-26-5)

Guidance literature:

With hydrogenchloride; In ethanol; for 24h; Ambient temperature;

Reference yield: 97.0%

tert-butyldicarbonate (34619-03-9) + ethyl 1-aminocyclobutanecarboxylate (285570-26-5) → ethyl 1-[(tert-butoxycarbonyl)amino]cyclobutanecarboxylate (163554-54-9)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 18.25h;

Reference yield:

ethyl 1-aminocyclobutanecarboxylate (285570-26-5) → 1-aminocyclobutanecarboxylic acid hydrochloride

Guidance literature:

With hydrogenchloride; water; for 2h; Reflux;

upstream raw materials:

ethyl 1-cyano-1-cyclobutanecarboxylate

Downstream raw materials:

ethyl 1-[(tert-butoxycarbonyl)amino]cyclobutanecarboxylate

Refernces