1H-Isoindole-1,3(2H)-dione, 2-octadecyl-

Base Information

• Chemical Name: 1H-Isoindole-1,3(2H)-dione, 2-octadecyl-
• CAS No.: 20332-12-1
• Molecular Formula: C26H41NO2
• Molecular Weight: 399.617
• European Community (EC) Number: 606-525-7
• DSSTox Substance ID: DTXSID50885127
• Nikkaji Number: J1.366.898A
• Wikidata: Q82863747
• Mol file: 20332-12-1.mol

Synonyms:20332-12-1;1H-Isoindole-1,3(2H)-dione, 2-octadecyl-;N-Octadecylphthalimide;SCHEMBL2121484;C26H41NO2;DTXSID50885127;2-Octadecylisoindoline-1,3-dione;BCZUGMNWRQGHFP-UHFFFAOYSA-N;C26-H41-N-O2;AKOS002077858;2-octadecyl-1H-isoindole-1,3(2H)-dione;1h-isoindole-1,3(2h)-dione,2-octadecyl-

Chemical Property of 1H-Isoindole-1,3(2H)-dione, 2-octadecyl-

Chemical Property:

• Vapor Pressure: 3.31E-10mmHg at 25°C
• Melting Point: 80-81 °C
• Refractive Index: 1.51
• Boiling Point: 502 °C at 760 mmHg
• PKA: -2.11±0.20(Predicted)
• Flash Point: 180.8 °C
• PSA: 37.38000
• Density: 0.988 g/cm³
• LogP: 7.48200
• XLogP3: 10.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 17
• Exact Mass: 399.313729551
• Heavy Atom Count: 29
• Complexity: 438

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCCCCN1C(=O)C2=CC=CC=C2C1=O

Technology Process of 1H-Isoindole-1,3(2H)-dione, 2-octadecyl-

There total 6 articles about 1H-Isoindole-1,3(2H)-dione, 2-octadecyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

potassium phtalimide (1074-82-4) + 1-Bromooctadecane (112-89-0) → 2-octadecylisoindoline-1,3-dione (20332-12-1)

Guidance literature:

In N,N-dimethyl-formamide; at 90 ℃; for 18h;

DOI:10.1021/acs.joc.8b00161

Reference yield: 92.0%

phthalic anhydride (85-44-9) + 1-aminooctadecane (124-30-1) → 2-octadecylisoindoline-1,3-dione (20332-12-1)

Guidance literature:

at 150 ℃; for 0.25h;

DOI:10.1016/S0040-4020(00)00445-2

Reference yield:

phthalic acid dimethyl ester (131-11-3,64441-70-9) + 1-aminooctadecane (124-30-1) → 2-octadecylisoindoline-1,3-dione (20332-12-1)

Guidance literature:

sodium methylate; In Solvesso 150; at 265 ℃; for 0.0102778h; under 26252.6 Torr; autoclave; Industry scale; Microwave irradiation;

upstream raw materials:

phthalic anhydride

1-aminooctadecane

phthalimide

n-octadecyl p-toluenesulfonate

Downstream raw materials:

[2-(hydroxymethyl)phenyl]-N-octadecylformamide

1-aminooctadecane

N-octadecylphthalamic acid

Refernces

• 1、 Gupta, Ravindra Kumar,Achalkumar, Ammathnadu S.. "Microwave-Assisted Method for the Synthesis of Perylene Ester Imides as a Gateway Toward Unsymmetrical Perylene Bisimides". supporting information. p. 6290 - 6300. Retrieved 2018/05/29.
• 2、 -. "1,2-di-substituted benzene-carboxamide derivative, hair growth promoter and external composition for skin using the same". . . Retrieved 2008/06/13.