2,6-DINITROANISOLE

Base Information

• Chemical Name: 2,6-DINITROANISOLE
• CAS No.: 3535-67-9
• Molecular Formula: C7H6 N2 O5
• Molecular Weight: 198.135
• Mol file: 3535-67-9.mol

Synonyms:Anisole,2,6-dinitro- (7CI,8CI); 2,6-Dinitroanisole; 2-Methoxy-1,3-dinitrobenzene

Chemical Property of 2,6-DINITROANISOLE

Chemical Property:

• Melting Point: 118°C
• Refractive Index: 1.5460 (estimate)
• Boiling Point: 335.43°C (rough estimate)
• PSA: 100.87000
• Density: 1.3000
• LogP: 2.55800

Purity/Quality:

99%min ^*data from raw suppliers

2,6-dinitrophenylmethylether ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2,6-Dinitrophenyl Methyl Ether is a binder; used in method for fabrication of granules of compressible explosive compound.

Technology Process of 2,6-DINITROANISOLE

There total 12 articles about 2,6-DINITROANISOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

sodium methylate (124-41-4) + 1-chloro-2,6-dinitrobenzene (606-21-3) → 2,6-dinitroanisole (3535-67-9)

Guidance literature:

In methanol; Heating / reflux;

Reference yield: 90.0%

methanol (67-56-1) + 2-bromo-1,3-dinitrobenzene (4185-79-9) → 2,6-dinitroanisole (3535-67-9)

Guidance literature:

With sodium; at 20 ℃; Inert atmosphere; Schlenk technique;

DOI:10.1021/om400114h

Reference yield: 47.0%

2-Methoxyphenylboronic acid (5720-06-9) → 2-Nitroanisole (91-23-6) + 2,4-dinitroanisole (119-27-7) + 2,6-dinitroanisole (3535-67-9)

Guidance literature:

With nitric acid; trifluoroacetic acid; In water; at 80 ℃; for 18h; regioselective reaction;

DOI:10.1080/00397911.2016.1244690

upstream raw materials:

2-Nitroanisole

1,2,3-trinitrobenzene

sodium methylate

methanol

Downstream raw materials:

2,2'-(2-Methoxyphenylen-1,3-diimino)-dibutensaeuretetramethylester

2,6-dinitrophenol

N-(2,6-dinitrophenyl)piperidine

2,6-dinitrophenoxide ion

Refernces

• 1、 Shen, Guodong,Zhao, Lingyu,Liu, Wanxing,Huang, Xianqiang,Song, Huina,Zhang, Tongxin. "Convenient, metal-free ipso-nitration of arylboronic acids using nitric acid and trifluoroacetic acid". supporting information. p. 10 - 14. Retrieved 2016/12/30.
• 2、 Reithofer, Michael R.,Dobereiner, Graham E.,Schrock, Richard R.,Mueller, Peter. "Monoaryloxide pyrrolide (MAP) imido alkylidene complexes of molybdenum and tungsten that contain 2,6-bis(2,5-R2-pyrrolyl) phenoxide (R = i-Pr, Ph) ligands and an unsubstituted metallacyclobutane on its way to losing ethylene". supporting information. p. 2489 - 2492. Retrieved 2013/06/27.