Benzothiazole, 2-(methylsulfinyl)- (7CI,8CI,9CI)

Base Information

• Chemical Name: Benzothiazole, 2-(methylsulfinyl)- (7CI,8CI,9CI)
• CAS No.: 3507-54-8
• Molecular Formula: C8H7 N O S2
• Molecular Weight: 197.282
• Mol file: 3507-54-8.mol

Synonyms:2-(Methylsulfinyl)benzothiazole

Chemical Property of Benzothiazole, 2-(methylsulfinyl)- (7CI,8CI,9CI)

Chemical Property:

• PSA: 77.41000
• LogP: 2.89940

Purity/Quality:

2-(METHYLSULFINYL)-BENZOTHIAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzothiazole, 2-(methylsulfinyl)- (7CI,8CI,9CI)

There total 5 articles about Benzothiazole, 2-(methylsulfinyl)- (7CI,8CI,9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.4%

2-methylmercaptobenzothiazole (615-22-5) → 2-(methylsulfinyl)benzothiazole (3507-54-8)

Guidance literature:

With 1,1'-dihydroperoxydicyclohexyl peroxide; In methanol; at 45 ℃; for 21h; Reagent/catalyst; Temperature; Time;

DOI:10.1016/j.tet.2021.132203

Reference yield: 84.0%

2-methylmercaptobenzothiazole (615-22-5) → 2-(methylsulfinyl)benzothiazole (3507-54-8) + 2-methanesulfonylbenzothiazole (7144-49-2)

Guidance literature:

2-methylmercaptobenzothiazole; With sodium tungstate (VI) dihydrate; In ethanol; at 0 ℃; for 0.0833333h; Inert atmosphere;

With dihydrogen peroxide; In ethanol; water; at 0 - 20 ℃; for 10.5h; Inert atmosphere;

DOI:10.1021/jo102326p

Reference yield: 61.0%

di-2-benzothiazolyl sulfoxide (119993-82-7) + methyl iodide (74-88-4) → 2-(methylsulfinyl)benzothiazole (3507-54-8)

Guidance literature:

With sodium ethanolate; In acetonitrile; Ambient temperature;

upstream raw materials:

2-methylmercaptobenzothiazole

di-2-benzothiazolyl sulfoxide

methyl iodide

2-Mercaptobenzothiazole

Downstream raw materials:

2-methylmercaptobenzothiazole

2-methanesulfonylbenzothiazole

2-hydroxybenzothiazole

2-(thiocyanomethylthio)benzothiazole

Refernces

• 1、 Frenzel, Romina A.,Romanelli, Gustavo P.,Blanco, Mirta N.,Pizzio, Luis R.. "Transition metal-modified polyoxometalates supported on carbon as catalyst in 2-(methylthio)-benzothiazole sulfoxidation". . p. 123 - 132. Retrieved 2015.
• 2、 Shi, Wenjun,Yu, Chunmian,Zhou, Xinrui,Zhu, Shihao. "Selective and mild sulfoxidation of 2-sulfylbenzothiazole using hydroperoxides derived from cyclohexanone in the absence of catalyst". . . Retrieved 2021/05/26.
• 3、 -. "Synthesis method of sulfoxide compound". Paragraph 0031-0033; 0107-0109. . Retrieved 2021/04/07.