Bis(2,4-dimethylphenyl)methanone

Base Information

• Chemical Name: Bis(2,4-dimethylphenyl)methanone
• CAS No.: 3478-88-4
• Molecular Formula: C17H18 O
• Molecular Weight: 238.329
• Hs Code.: 2914399090
• European Community (EC) Number: 675-811-1
• DSSTox Substance ID: DTXSID80483574
• Nikkaji Number: J209.055D
• Wikidata: Q82320986
• Mol file: 3478-88-4.mol

Synonyms:bis(2,4-dimethylphenyl)methanone;3478-88-4;2,2',4,4'-Tetramethylbenzophenone;MFCD00060094;SCHEMBL286054;di-(2,4-dimethylphenyl) ketone;DTXSID80483574;KFNQSAKXSGGDAA-UHFFFAOYSA-N;2,2',4,4'tetramethylbenzophenone;AKOS005920171;AS-60957;SY053813;CS-0187323;FT-0653785;T1232;D97415;A822400;2,2 inverted exclamation mark ,4,4 inverted exclamation mark -Tetramethylbenzophenone

Chemical Property of Bis(2,4-dimethylphenyl)methanone

Chemical Property:

• Melting Point: 88-90 °C
• Refractive Index: 1.5830-1.5860
• Boiling Point: 188 °C / 7mmHg
• Flash Point: 146.7oC
• PSA: 17.07000
• Density: 1,04 g/cm3
• LogP: 4.15120
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 4.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 238.135765193
• Heavy Atom Count: 18
• Complexity: 268

Purity/Quality:

98% ^*data from raw suppliers

2,2'',4,4''-Tetramethylbenzophenone ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1)C(=O)C2=C(C=C(C=C2)C)C)C

Technology Process of Bis(2,4-dimethylphenyl)methanone

There total 17 articles about Bis(2,4-dimethylphenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2,4-dimethylbenzaldehyde (15764-16-6) → 2,2',4,4'-tetramethylbenzophenone (3478-88-4)

Guidance literature:

With di(rhodium)tetracarbonyl dichloride; di-tert-butyl peroxide; 1,2-bis-(diphenylphosphino)ethane; In benzene; at 160 ℃; for 12h; chemoselective reaction; Inert atmosphere;

DOI:10.1039/c0cc04921b

Reference yield: 70.0%

carbon monoxide (201230-82-2) + potassium (2,4-dimethylphenyl) trifluoroborate → 2,2',4,4'-tetramethylbenzophenone (3478-88-4)

Guidance literature:

With iodine; palladium diacetate; sodium carbonate; at 80 ℃; for 15h; under 760.051 Torr;

DOI:10.1002/ejoc.201600689

Reference yield: 65.0%

carbon monoxide (201230-82-2) + m-xylene (108-38-3,104809-90-7) → 2,2',4,4'-tetramethylbenzophenone (3478-88-4)

Guidance literature:

With bis(η3-allyl-μ-chloropalladium(II)); iodine; silver trifluoromethanesulfonate; In 1,2-dichloro-ethane; at 60 ℃; for 22h; under 3040.2 Torr;

DOI:10.1039/d0sc00085j

upstream raw materials:

tetrachloromethane

m-xylene

phosgene

methylammonium carbonate

Downstream raw materials:

4,4'-carbonyl-di-isophthalic acid

bis(2,4-dimethylphenyl)methanol

1,1-bis-(2,4-dimethyl-phenyl)-ethene

1,1-bis(2,4-dimethylphenyl)-2-propyn-1-ol

Refernces

• 1、 Zhao, Hongyuan,Han, Wei. "Ligand-Free Palladium-Catalyzed Oxidative Carbonylative Homocoupling of Arylboron Reagents at Ambient Pressure". supporting information. p. 4279 - 4283. Retrieved 2016/09/14.