(E)-3-(2-furyl)-2-cyanoprop-2-enethioamide

Base Information

• Chemical Name: (E)-3-(2-furyl)-2-cyanoprop-2-enethioamide
• CAS No.: 68029-49-2
• Molecular Formula: C₈H₆N₂OS
• Molecular Weight: 178.214
• Mol file: 68029-49-2.mol

Synonyms:(E)-3-(2-furyl)-2-cyanoprop-2-enethioamide

Chemical Property of (E)-3-(2-furyl)-2-cyanoprop-2-enethioamide

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

(E)-2-CYANO-3-(2-FURYL)PROP-2-ENE THIOAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-3-(2-furyl)-2-cyanoprop-2-enethioamide

There total 1 articles about (E)-3-(2-furyl)-2-cyanoprop-2-enethioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

furfural (98-01-1) + Cyanothioacetamide (7357-70-2) → (E)-3-(2-furyl)-2-cyanoprop-2-enethioamide (68029-49-2)

Guidance literature:

With aluminum oxide; In methanol; at 20 ℃; for 24h;

DOI:10.1080/00397919308013782

Reference yield: 90.0%

(E)-3-(2-furyl)-2-cyanoprop-2-enethioamide (68029-49-2) + 2-bromo-1-(3,4-dichlorophenyl)ethanone (2632-10-2) → C16H8Cl2N2OS (332175-19-6)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 24.5h;

DOI:10.1134/S1070363215040167

Reference yield: 88.0%

4-methyl-morpholine (109-02-4) + 2'-methoxyacetoacetanilide (92-15-9) + (E)-3-(2-furyl)-2-cyanoprop-2-enethioamide (68029-49-2) → 5-Cyano-4-furan-2-yl-6-mercapto-2-methyl-1,4-dihydro-pyridine-3-carboxylic acid (2-methoxy-phenyl)-amide; compound with 4-methyl-morpholine

Guidance literature:

In ethanol; at 20 ℃; for 6h;

upstream raw materials:

furfural

Cyanothioacetamide

Downstream raw materials:

3-cyano-4-(2'-furyl)-6-phenylpyridinethione

Cyanothioacetamide

6-Allylsulfanyl-5-cyano-4-furan-2-yl-2-methyl-1,4-dihydro-pyridine-3-carboxylic acid (2-methoxy-phenyl)-amide

Refernces

• 1、 Villemin,Martin. "Condensation of α-cyanothioacetamide with aldehydes catalysed by alumina". . p. 2259 - 2263. Retrieved 2007/10/02.