2-chloroethyl 2-sulfamoylbenzoate

Base Information

• Chemical Name: 2-chloroethyl 2-sulfamoylbenzoate
• CAS No.: 79945-17-8
• Molecular Formula: C₉H₁₀ClNO₄S
• Molecular Weight: 263.702
• Mol file: 79945-17-8.mol

Synonyms:2-chloroethyl 2-sulfamoylbenzoate

Chemical Property of 2-chloroethyl 2-sulfamoylbenzoate

Chemical Property:

Purity/Quality:

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Technology Process of 2-chloroethyl 2-sulfamoylbenzoate

There total 1 articles about 2-chloroethyl 2-sulfamoylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

2-hydroxyethyl 2-sulfamoylbenzoate → 2-chloroethyl 2-sulfamoylbenzoate (79945-17-8)

Guidance literature:

With thionyl chloride; triethylamine; In chloroform; at 0 ℃; for 3.5h; Reflux;

DOI:10.1021/jm301501k

Reference yield:

oxalyl dichloride (79-37-8) + 2-chloroethyl 2-sulfamoylbenzoate (79945-17-8) → 2-(β-chloroethoxycarbonyl)benzenesulfonyl isocyanate

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; In toluene; at 20 - 100 ℃;

DOI:10.1021/jm301501k

Reference yield:

2-chloroethyl 2-sulfamoylbenzoate (79945-17-8) → C15H14Cl2N4O6S (1416567-36-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 1,4-diaza-bicyclo[2.2.2]octane / toluene / 20 - 100 °C

2: acetonitrile / 12 h / 20 °C

With 1,4-diaza-bicyclo[2.2.2]octane; In toluene; acetonitrile;

DOI:10.1021/jm301501k

Downstream raw materials:

C₁₅H₁₄Cl₂N₄O₆S

C₁₅H₁₄ClIN₄O₆S

C₁₅H₁₄BrClN₄O₆S

Refernces