4-Hydroxy-3,5-diphenylbenzaldehyde

Base Information

• Chemical Name: 4-Hydroxy-3,5-diphenylbenzaldehyde
• CAS No.: 3437-80-7
• Molecular Formula: C19H14 O2
• Molecular Weight: 274.319
• Hs Code.: 2912491000
• DSSTox Substance ID: DTXSID10438658
• Nikkaji Number: J1.254.988A
• Wikidata: Q82254464
• Mol file: 3437-80-7.mol

Synonyms:3437-80-7;4-HYDROXY-3,5-DIPHENYLBENZALDEHYDE;3,5-DIPHENYL-4-HYDROXYBENZALDEHYDE;Benzaldehyde,4-hydroxy-3,5-bis(3-methyl-2-butenyl)-;SCHEMBL9472211;2'-hydroxy-[1,1':3',1''-terphenyl]-5'-carbaldehyde;DTXSID10438658;2'-Hydroxy-1,1':3',1''-terbenzene-5'-carbaldehyde;2'-hydroxy[1,1':3',1''] terphenyl-5'-carbaldehyde;2~2~-Hydroxy[1~1~,2~1~:2~3~,3~1~-terphenyl]-2~5~-carbaldehyde

Chemical Property of 4-Hydroxy-3,5-diphenylbenzaldehyde

Chemical Property:

• PSA: 37.30000
• LogP: 4.53870
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 274.099379685
• Heavy Atom Count: 21
• Complexity: 301

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC(=CC(=C2O)C3=CC=CC=C3)C=O

Technology Process of 4-Hydroxy-3,5-diphenylbenzaldehyde

There total 1 articles about 4-Hydroxy-3,5-diphenylbenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-diphenyl-4-methylphenol (75850-21-4) + methoxybenzene (100-66-3) → 2'-hydroxy[1,1';3',1'']terphenyl-5'-carbaldehyde (3437-80-7) + 5'-(2-methoxy-benzyl)-[1,1';3',1'']terphenyl-2'-ol + 5'-(4-methoxy-benzyl)-[1,1';3',1'']terphenyl-2'-ol

Guidance literature:

With N-Bromosuccinimide; zinc(II) chloride; In tetrachloromethane; at 120 ℃; for 4h;

DOI:10.1021/jo9911185

Reference yield: 89.0%

1H-indene-1,3(2H)-dione (606-23-5) + 2'-hydroxy[1,1';3',1'']terphenyl-5'-carbaldehyde (3437-80-7) + 1-amino-naphthalene (134-32-7) → 7-(2'-hydroxy-1,1':3',1''-terphenyl-5'-yl)-7,13-dihydro-8H-benzo[h]indeno[1,2-b]quinolin-8-one (1217079-97-4)

Guidance literature:

2'-hydroxy[1,1';3',1'']terphenyl-5'-carbaldehyde; 1-amino-naphthalene; In ethanol; for 0.25h; Reflux;

1H-indene-1,3(2H)-dione; In ethanol; for 1h; Reflux;

DOI:10.1134/S1070428009100133

Reference yield: 86.0%

2'-hydroxy[1,1';3',1'']terphenyl-5'-carbaldehyde (3437-80-7) + 1,3-cylohexanedione (504-02-9) + 1-amino-naphthalene (134-32-7) → 7-(2'-hydroxy-1,1':3',1''-terphenyl-5'-yl)-7,8,9,10,11,12-hexahydrobenzo[c]acridin-8-one (1217079-84-9)

Guidance literature:

2'-hydroxy[1,1';3',1'']terphenyl-5'-carbaldehyde; 1-amino-naphthalene; In ethanol; for 0.25h; Reflux;

1,3-cylohexanedione; In ethanol; for 5h; Reflux;

DOI:10.1134/S1070428009100133

upstream raw materials:

2,6-diphenyl-4-methylphenol

methoxybenzene

Downstream raw materials:

1-(3,5-diphenyl-4-hydroxyphenyl)-2-phenylethanol

(4-hydroxy-3,5-diphenylphenyl)(phenyl)methanol

(4-hydroxy-3,5-diphenylphenyl)(4-methoxyphenyl)methanol

(4-hydroxy-3,5-diphenylphenyl)[4-(dimethylamino)phenyl]methanol

Refernces