Technology Process of C26H24FN5O3
There total 3 articles about C26H24FN5O3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate;
In
tetrahydrofuran; water;
at 40 ℃;
for 16h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: water; toluene-4-sulfonic acid / methanol / 2 h / 20 °C
2: toluene-4-sulfonic acid / 5,5-dimethyl-1,3-cyclohexadiene; water / 25 h / Reflux
3: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate / tetrahydrofuran; water / 16 h / 40 °C / Inert atmosphere
With
dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; water; palladium diacetate; toluene-4-sulfonic acid;
In
tetrahydrofuran; methanol; 5,5-dimethyl-1,3-cyclohexadiene; water;
3: |Suzuki Coupling;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: toluene-4-sulfonic acid / 5,5-dimethyl-1,3-cyclohexadiene; water / 25 h / Reflux
2: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate / tetrahydrofuran; water / 16 h / 40 °C / Inert atmosphere
With
dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate; toluene-4-sulfonic acid;
In
tetrahydrofuran; 5,5-dimethyl-1,3-cyclohexadiene; water;
2: |Suzuki Coupling;