(24S)-cholest-5-ene-3β,7α,24-triol 3β,24-dibenzoate

Base Information

• Chemical Name: (24S)-cholest-5-ene-3β,7α,24-triol 3β,24-dibenzoate
• CAS No.: 306288-46-0
• Molecular Formula: C₄₁H₅₄O₅
• Molecular Weight: 626.877
• Mol file: 306288-46-0.mol

Synonyms:(24S)-cholest-5-ene-3β,7α,24-triol 3β,24-dibenzoate

Chemical Property of (24S)-cholest-5-ene-3β,7α,24-triol 3β,24-dibenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (24S)-cholest-5-ene-3β,7α,24-triol 3β,24-dibenzoate

There total 4 articles about (24S)-cholest-5-ene-3β,7α,24-triol 3β,24-dibenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

(24S)-7-oxocholest-5-en-3β,24-diyl dibenzoate (306288-43-7) → (24S)-cholest-5-ene-3β,7α,24-triol 3β,24-dibenzoate (306288-46-0)

Guidance literature:

With L-Selectride; In tetrahydrofuran; at -78 ℃; for 3h;

DOI:10.1016/S0039-128X(00)00131-8

Reference yield:

24(S)-hydroxycholesterol (474-73-7) → (24S)-cholest-5-ene-3β,7α,24-triol 3β,24-dibenzoate (306288-46-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 86 percent / pyridine / 20 °C

2: 78 percent / pyridine; CrO₃ / CH₂Cl₂ / Heating

3: 69 percent / L-Selectride / tetrahydrofuran / 3 h / -78 °C

With pyridine; chromium(VI) oxide; L-Selectride; In tetrahydrofuran; dichloromethane;

DOI:10.1016/S0039-128X(00)00131-8

Reference yield:

(24S)-cholest-5-ene-3β,24-diyl dibenzoate (27460-29-3) → (24S)-cholest-5-ene-3β,7α,24-triol 3β,24-dibenzoate (306288-46-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / pyridine; CrO₃ / CH₂Cl₂ / Heating

2: 69 percent / L-Selectride / tetrahydrofuran / 3 h / -78 °C

With pyridine; chromium(VI) oxide; L-Selectride; In tetrahydrofuran; dichloromethane;

DOI:10.1016/S0039-128X(00)00131-8

upstream raw materials:

(24S)-7-oxocholest-5-en-3β,24-diyl dibenzoate

24(S)-hydroxycholesterol

(24S)-cholest-5-ene-3β,24-diyl dibenzoate

benzoyl chloride

Refernces