tert-Butoxycarbonylamino-cyclohexyl-acetic acid

Base Information Edit

Chemical Name:tert-Butoxycarbonylamino-cyclohexyl-acetic acid
CAS No.:35264-05-2
Molecular Formula:C13H23 N O4
Molecular Weight:257.33
Hs Code.:2924299090
European Community (EC) Number:674-646-2
DSSTox Substance ID:DTXSID60393627
Mol file:35264-05-2.mol

Synonyms:35264-05-2;tert-Butoxycarbonylamino-cyclohexyl-acetic acid;N-Boc-2-Cyclohexyl-DL-glycine;2-((tert-Butoxycarbonyl)amino)-2-cyclohexylacetic acid;N-Boc-2-Cyclohexylglycine;2-cyclohexyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]acetic Acid;2-(tert-butoxycarbonylamino)-2-cyclohexylacetic acid;MFCD04115511;[(tert-butoxycarbonyl)amino](cyclohexyl)acetic acid;(R)-2-(Boc-amino)-2-cyclohexylacetic Acid;boc-dl-cyclohexylglycine;SCHEMBL844823;2-((tert-Butoxycarbonyl)amino)-2-cyclohexylaceticacid;2-{[(tert-butoxy)carbonyl]amino}-2-cyclohexylacetic acid;DTXSID60393627;QSUXZIPXYDQFCX-UHFFFAOYSA-N;AKOS009157396;AB20151;AM84915;HY-W021790;SB16143;SB16144;2-(Boc-amino)-2-cyclohexylacetic Acid;AC-24586;BS-12325;PD196396;SY016297;SY020834;SY035104;tert-butoxycarbonylaminocyclohexylacetic acid;A6192;CS-0041383;FT-0630057;FT-0641299;FT-0679753;Tert-butoxycarbonylamino-cyclohexyl-aceticacid;EN300-96379;tert-butoxycarbonylamino(cyclohexyl)acetic acid;A836899;A920651;Z728897758;2-[(2-tert-butoxycarbonylcyclohexyl)amino]acetic acid;Boc-D-cyclohexylglycine;N-Boc-2-cyclohexyl-l-glycinE;(S)-Tert-butoxycarbonylamino-cyclohexyl-acetic acid

Suppliers and Price of tert-Butoxycarbonylamino-cyclohexyl-acetic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Boc-DL-cyclohexylglycine
50g
$ 605.00

Crysdot
2-((tert-Butoxycarbonyl)amino)-2-cyclohexylaceticacid 97%
100g
$ 594.00

Chemenu
2-(tert-Butoxycarbonylamino)-2-cyclohexylaceticacid 97%
100g
$ 561.00

Chemenu
2-(tert-Butoxycarbonylamino)-2-cyclohexylaceticacid 97%
25g
$ 204.00

Chemenu
2-(tert-Butoxycarbonylamino)-2-cyclohexylaceticacid 97%
10g
$ 102.00

AstaTech
N-BOC-2-CYCLOHEXYL-DL-GLYCINE 97%
100 / G
$ 600.00

AstaTech
N-BOC-2-CYCLOHEXYL-DL-GLYCINE 97%
5 / G
$ 80.00

AstaTech
N-BOC-2-CYCLOHEXYL-DL-GLYCINE 97%
25 / G
$ 240.00

Apolloscientific
Boc-2-Cyclohexylglycine 97%
25g
$ 544.00

Apolloscientific
Boc-2-Cyclohexylglycine 97%
1g
$ 106.00

Total 38 raw suppliers

Chemical Property of tert-Butoxycarbonylamino-cyclohexyl-acetic acid Edit

Chemical Property:

Vapor Pressure:8.56E-08mmHg at 25°C
Refractive Index:1.49
Boiling Point:407.9°Cat760mmHg
Flash Point:200.5°C
PSA：75.63000
Density:1.111g/cm³
LogP:2.93550
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:257.16270821
Heavy Atom Count:18
Complexity:303

Purity/Quality:

99% ^*data from raw suppliers

N-Boc-DL-cyclohexylglycine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(C1CCCCC1)C(=O)O
Uses N-Boc-DL-cyclohexylglycine has been used as a reactant in the preparation of SCH 503034, an orally bioavailable NS3 protease inhibitor.

Technology Process of tert-Butoxycarbonylamino-cyclohexyl-acetic acid

There total 5 articles about tert-Butoxycarbonylamino-cyclohexyl-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 124-38-9,18923-20-1
carbon dioxide

: 253426-70-9
tert-butyl cyclohexyl(phenylsulfonyl)methylcarbamate

: 35264-05-2
2-((tert-butoxycarbonyl)amino)-2-cyclohexylacetic acid

Guidance literature:: With tetrabutyl ammonium fluoride; In N,N-dimethyl-formamide; at 0 ℃; under 760.051 Torr; Electrochemical reaction;
DOI:10.1021/acs.joc.1c01516