Technology Process of C28H29Cl2FN6O3
There total 7 articles about C28H29Cl2FN6O3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); potassium fluoride dihydrate;
In
1,2-dimethoxyethane; ethanol; water;
at 110 ℃;
for 0.833333h;
Microwave irradiation;
DOI:10.1016/j.bmc.2012.07.007
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium tetrahydroborate / methanol / 2 h / 20 °C
2.1: triethylamine; dmap / dichloromethane / 1 h / 0 °C
3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 °C
3.2: 4 h / 80 °C
4.1: tetrakis(triphenylphosphine) palladium(0); potassium fluoride dihydrate / water; ethanol; 1,2-dimethoxyethane / 0.83 h / 110 °C / Microwave irradiation
With
dmap; sodium tetrahydroborate; tetrakis(triphenylphosphine) palladium(0); potassium fluoride dihydrate; sodium hydride; triethylamine;
In
methanol; 1,2-dimethoxyethane; ethanol; dichloromethane; water; N,N-dimethyl-formamide; mineral oil;
4.1: |Suzuki Coupling;
DOI:10.1016/j.bmc.2012.07.007
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: acetic acid; bromine / 0.5 h / 20 °C
2.1: 0.5 h / 150 °C / Microwave irradiation
3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 °C
3.2: 4 h / 80 °C
4.1: tetrakis(triphenylphosphine) palladium(0); potassium fluoride dihydrate / water; ethanol; 1,2-dimethoxyethane / 0.83 h / 110 °C / Microwave irradiation
With
tetrakis(triphenylphosphine) palladium(0); potassium fluoride dihydrate; bromine; sodium hydride; acetic acid;
In
1,2-dimethoxyethane; ethanol; water; N,N-dimethyl-formamide; mineral oil;
4.1: |Suzuki Coupling;
DOI:10.1016/j.bmc.2012.07.007