Pentachlorophenyl 2,3,4,6-tetra-O-acetyl-β-D-galactose

Base Information

• Chemical Name: Pentachlorophenyl 2,3,4,6-tetra-O-acetyl-β-D-galactose
• CAS No.: 91876-32-3
• Molecular Formula: C₂₀H₁₉Cl₅O₁₀
• Molecular Weight: 596.63
• Mol file: 91876-32-3.mol

Synonyms:Pentachlorophenyl 2,3,4,6-tetra-O-acetyl-β-D-galactose

Chemical Property of Pentachlorophenyl 2,3,4,6-tetra-O-acetyl-β-D-galactose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Pentachlorophenyl 2,3,4,6-tetra-O-acetyl-β-D-galactose

There total 1 articles about Pentachlorophenyl 2,3,4,6-tetra-O-acetyl-β-D-galactose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

sodium pentachlorphenate (131-52-2) + 1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside (3068-32-4) → Pentachlorophenyl 2,3,4,6-tetra-O-acetyl-β-D-galactose (91876-32-3)

Guidance literature:

In acetone; for 2h; Heating;

Reference yield: 75.0%

Pentachlorophenyl 2,3,4,6-tetra-O-acetyl-β-D-galactose (91876-32-3) → 1,6-anhydro-β-D-galactopyranose (644-76-8)

Guidance literature:

With potassium hydroxide; for 1h; Heating;

Reference yield:

Pentachlorophenyl 2,3,4,6-tetra-O-acetyl-β-D-galactose (91876-32-3) → (6S)-(6-2H1)-1,6-Anhydro-2,3,4-tri-O-benzoyl-β-D-galactopyranose (86448-06-8,86448-14-8,91876-35-6,110567-09-4,110567-10-7,110567-11-8,110567-12-9,110567-13-0,110567-14-1,110567-15-2,110567-16-3,110567-17-4,110567-18-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 75 percent / aq. KOH / 1 h / Heating

2: 94 percent / pyridine

3: 86 percent / Br₂, CCl₄ / 2 h / Heating; Irradiation

4: 97 percent / tri-n-butyltin deuteride, azobisisobutyronitrile / toluene / 1 h / Heating

With pyridine; tetrachloromethane; potassium hydroxide; 2,2'-azobis(isobutyronitrile); bromine; tributyltin deuteride; In toluene;

upstream raw materials:

sodium pentachlorphenate

1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside

Downstream raw materials:

1,6-anhydro-β-D-galactopyranose

(6S)-(6-2H1)-1,6-Anhydro-2,3,4-tri-O-benzoyl-β-D-galactopyranose

(6S)-1,6-Anhydro-2,3,4-tri-O-benzoyl-6-bromo-β-D-galactopyranose

1,6-Anhydro-2,3,4-tri-O-benzoyl-β-D-galactopyranose

Refernces