N-benzyl-N-methyloctanamide

Base Information

• Chemical Name: N-benzyl-N-methyloctanamide
• CAS No.: 1315320-39-8
• Molecular Formula: C₁₆H₂₅NO
• Molecular Weight: 247.381
• Mol file: 1315320-39-8.mol

Synonyms:N-benzyl-N-methyloctanamide

Chemical Property of N-benzyl-N-methyloctanamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-benzyl-N-methyloctanamide

There total 1 articles about N-benzyl-N-methyloctanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

benzyl-methyl-amine (103-67-3) + n-octanoic acid chloride (111-64-8) → N-benzyl-N-methyloctanamide (1315320-39-8)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 1h; Inert atmosphere;

DOI:10.1021/ol3000316

Reference yield: 97.0%

N-benzyl-N-methyloctanamide (1315320-39-8) → N-methyloctanoylamide (1119-57-9)

Guidance literature:

With 15-crown-5; sodium; isopropyl alcohol; In tetrahydrofuran; at 0 ℃; for 0.5h; chemoselective reaction;

DOI:10.1021/acs.orglett.8b00891

Reference yield: 86.0%

N-benzyl-N-methyloctanamide (1315320-39-8) + allyltributylstanane (24850-33-7) → N-benzyl-N-methylundec-1-en-4-amine (1315320-52-5)

Guidance literature:

N-benzyl-N-methyloctanamide; With zirconocene dichloride; sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; 1,2-dichloro-ethane; toluene; at 20 ℃; for 0.25h; Inert atmosphere;

allyltributylstanane; With acetonitrile; trifluoroacetic acid; In tetrahydrofuran; toluene; at 20 ℃; for 24h; chemoselective reaction; Inert atmosphere;

DOI:10.1021/ol3000316

upstream raw materials:

benzyl-methyl-amine

n-octanoic acid chloride

Downstream raw materials:

N-benzyl-N-methylundec-1-en-4-amine

N-methyl,N-(n-octyl) benzylamine

N-methyloctanoylamide

Refernces