4-((4-ethanoylphenylcarbamoyloxy)methyl)-1-methylpyridinium trifluoromethanesulfonate

Base Information

• Chemical Name: 4-((4-ethanoylphenylcarbamoyloxy)methyl)-1-methylpyridinium trifluoromethanesulfonate
• CAS No.: 1345959-46-7
• Molecular Formula: CF₃O₃S*C₁₆H₁₇N₂O₃
• Molecular Weight: 434.393
• Mol file: 1345959-46-7.mol

Synonyms:4-((4-ethanoylphenylcarbamoyloxy)methyl)-1-methylpyridinium trifluoromethanesulfonate

Chemical Property of 4-((4-ethanoylphenylcarbamoyloxy)methyl)-1-methylpyridinium trifluoromethanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-((4-ethanoylphenylcarbamoyloxy)methyl)-1-methylpyridinium trifluoromethanesulfonate

There total 3 articles about 4-((4-ethanoylphenylcarbamoyloxy)methyl)-1-methylpyridinium trifluoromethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

4-(((1H-imidazole-1-carbonyl)oxy)methyl)-1-methylpyridin-1-ium trifluoromethanesulfonate (1345959-29-6) + p-aminobenzophenone (99-92-3) → 4-((4-ethanoylphenylcarbamoyloxy)methyl)-1-methylpyridinium trifluoromethanesulfonate (1345959-46-7)

Guidance literature:

In acetonitrile; at 60 ℃;

DOI:10.1021/ol202456d

Reference yield:

4-(hydroxymethyl)-1-methylpyridin-1-ium iodide (6457-57-4) → 4-((4-ethanoylphenylcarbamoyloxy)methyl)-1-methylpyridinium trifluoromethanesulfonate (1345959-46-7)

Guidance literature:

Multi-step reaction with 3 steps

1: acetonitrile / -30 °C

2: acetonitrile / 1 h

3: acetonitrile / 60 °C

In acetonitrile;

DOI:10.1021/ol202456d

Reference yield:

4-(((1H-imidazole-1-carbonyl)oxy)methyl)-1-methylpyridin-1-ium iodide (1345959-27-4) → 4-((4-ethanoylphenylcarbamoyloxy)methyl)-1-methylpyridinium trifluoromethanesulfonate (1345959-46-7)

Guidance literature:

Multi-step reaction with 2 steps

1: acetonitrile / 1 h

2: acetonitrile / 60 °C

In acetonitrile;

DOI:10.1021/ol202456d

upstream raw materials:

4-(((1H-imidazole-1-carbonyl)oxy)methyl)-1-methylpyridin-1-ium iodide

4-(((1H-imidazole-1-carbonyl)oxy)methyl)-1-methylpyridin-1-ium trifluoromethanesulfonate

p-aminobenzophenone

4-(hydroxymethyl)-1-methylpyridin-1-ium iodide

Downstream raw materials:

p-aminobenzophenone

Refernces