5-acetoxyflavone

Base Information

• Chemical Name: 5-acetoxyflavone
• CAS No.: 93327-97-0
• Molecular Formula: C₁₇H₁₂O₄
• Molecular Weight: 280.28
• Mol file: 93327-97-0.mol

Synonyms:5-acetoxyflavone

Chemical Property of 5-acetoxyflavone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 5-acetoxyflavone

There total 11 articles about 5-acetoxyflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.3%

5-Hydroxyflavone (491-78-1,66585-06-6) + acetyl chloride (75-36-5) → 5-acetoxyflavone (93327-97-0)

Guidance literature:

With potassium carbonate; In dichloromethane; at 20 ℃;

Reference yield:

5-Hydroxyflavone (491-78-1,66585-06-6) + acetic anhydride (108-24-7) → 5-acetoxyflavone (93327-97-0)

Guidance literature:

With sodium acetate;

Reference yield:

2-hydroxy-1-(2-hydroxyphenyl)ethanone (17375-96-1) → 5-acetoxyflavone (93327-97-0)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / acetone / 12 h / 55 °C

2: sulfuric acid / 4 h / Cooling with ice

3: potassium carbonate / dichloromethane / 20 °C

With sulfuric acid; potassium carbonate; In dichloromethane; acetone;

upstream raw materials:

5-Hydroxyflavone

acetic anhydride

2,6-dihydroxylacetophenone

8-acetyl-7-hydroxy-4-methyl-2H-chromen-2-one

Downstream raw materials:

6-acetyl-5-hydroxy-2-phenyl-chromen-4-one

5-Hydroxyflavone

Refernces